在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FGFR1OP Antibody

  • 中文名稱:
    FGFR1OP兔多克隆抗體
  • 貨號:
    CSB-PA008643GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    FGFR1OP
  • 別名:
    FGFR1 oncogene partner antibody; FGFR1OP antibody; Fibroblast growth factor receptor 1 oncogene partner antibody; FOP antibody; FR1OP_HUMAN antibody; OTTHUMP00000017612 antibody; OTTHUMP00000017613 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human FGFR1OP
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for anchoring microtubules to the centrosomes. Required for ciliation.
  • 基因功能參考文獻:
    1. The rs151606 T>G was associated with an increased risk of lung cancer and rs12212247 T>C was associated with a decreased risk of lung cancer PMID: 26905588
    2. This study was designed to determine the association of CCR6 and FGFR10P (tag)single nucleotide polymorphisms with Vogt-Koyanagi-Harada (VKH) syndrome, in two independent Chinese Han populations. PMID: 23935994
    3. FOP is a centriolar satellite protein involved in ciliogenesis. PMID: 23554904
    4. CAP350 interacts directly with FOP (FGFR1 oncogene partner) to form a centrosomal complex required for microtubule anchoring. PMID: 16314388
    5. a 1.6A resolution crystal structure of the N-terminal dimerization domain of FOP. The structure comprises an alpha-helical bundle composed of two antiparallel chains, each of them having five alpha-helices. PMID: 16690081
    6. Since FGFR1OP is plays a significant role in lung cancer growth and progression, it may be useful as a prognostic biomarker and as a therapeutic target for lung cancer. PMID: 17888034

    顯示更多

    收起更多

  • 相關疾病:
    A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity (PubMed:9949182).
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族:
    FGFR1OP family
  • 組織特異性:
    Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas.
  • 數據庫鏈接:

    HGNC: 17012

    OMIM: 605392

    KEGG: hsa:11116

    STRING: 9606.ENSP00000355812

    UniGene: Hs.487175



主站蜘蛛池模板: 亚洲欧美成αⅴ人在线观看| 国产精品久久久久野外| 性欧美丰满熟妇xxxx性久久久| 少妇午夜福利一区二区| 一区二三区国产好的精华液o9| 国产亚洲精品a在线无码| 伊人久久综合色| 欧美裸体xxxx极品少妇| 欧美亚洲日韩国产网站| 免费无码又爽又刺激软件下载| 丝袜美腿亚洲一区二区| 亚洲国产精品尤物yw在线观看| 免费无码精品黄av电影| 亚洲国产欧美国产综合一区| 日产精品一区2区卡四卡二卡| 色欲来吧来吧天天综合网| 亚洲欧美不卡高清在线| 性一交一黄一片| 日本护士╳╳╳hd少妇| 粉嫩虎白女毛片人体| 精品无码乱码av| 国产第一页浮力影院草草| 大陆国语对白国产av片| 中文字幕精品一区二区精品| av天堂中av世界中文在线播放| 亚洲最大成人网 色香蕉| 欧美日本日韩| 国产亚洲精品aaaa片app| a∨变态另类天堂无码专区| 亚洲人禽杂交av片久久| 一本一久本久a久久精品综合| 欧美精品久久天天躁| 国产亚洲日本精品成人专区| 熟女丝袜潮喷内裤视频网站| 精品人妻系列无码一区二区三区 | 天天躁夜夜躁狠狠综合| 亚洲国产美女精品久久久久| 国产999精品久久久久久| 久久精品无码免费不卡| 国产制服丝袜欧美在线观看| 亚洲人成在线影院|