在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FGF3 Antibody

  • 中文名稱:
    FGF3兔多克隆抗體
  • 貨號:
    CSB-PA266668
  • 規格:
    ¥2024
  • 圖片:
    • Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FGF3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide corresponding to residues near the C terminal of Human fibroblast growth factor 3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development.
  • 基因功能參考文獻:
    1. FGFR1 and/or FGF3 gene amplification correlated with a lower pathologic complete response in patients with HER2(+) early breast cancer treated with neoadjuvant anti-HER2 therapy PMID: 28381415
    2. fibroblast growth factor receptor 3 missense mutations were identified in 5 cases of thanatophoric dysplasia PMID: 28249712
    3. MCF7 cells over-expressing both WNT1 and FGF3 show a 3.5-fold increase in mammosphere formation; conditioned media from these cells also promotes stem cell activity in untransfected parental MCF7 and T47D cells, as WNT1 and FGF3 are secreted factors. PMID: 26421711
    4. analysis provided evidence for gene-gene interaction between FGF3 (rs4980700) and PAX9 (rs2073242), increasing risk for isolated oral clefts (p = 0.0003). FGF3 is associated with oral clefts and may interact with PAX9. PMID: 24697712
    5. haplotypes may contribute to the tendon disease process in elite volleyball athletes PMID: 24661680
    6. FGF3 gene expression is altered in a human breast cancer progression model. PMID: 25333703
    7. Higher FGF-23 concentration was associated with LVED mass and with incident atrial fibrillation and may, in part, explain the link between chronic kidney disease and AF. PMID: 24920722
    8. A de novo 290 kb interstitial duplication of chromosome 11q13.3 including the FGF3 and FGF4 genes. PMID: 24120895
    9. tooth agenesis had increased risk of a family history of cancer. tooth agenesis was associated with positive self-reported family history of cancer and variants in FGF3. PMID: 23169889
    10. This study is the first to show a significant association between coronary calcification and elevated serum FGF 23 in children. PMID: 21359960
    11. confirm the absence of otodental syndrome in heterozygous FGF3 carriers, but report unilateral microtia in one of them PMID: 21480479
    12. Manifestations of recessive FGF3 mutations range from fully penetrant LAMM syndrome to deafness with residual inner ear structures and, by extension, with minimal syndromic features. PMID: 21306635
    13. alterations in dosage of the Fgf3 gene cause dental morphological changes PMID: 20018768
    14. labyrinth aplasia, microtia, and microdontia (LAMM) syndrome, caused by mutations in FGF3 PMID: 19950373
    15. These findings suggest that the nuclear form of FGF3 inhibits cell proliferation by interfering with ribosomal biogenesis. PMID: 16263090
    16. Development of the inner ear is completely disturbed at a very early stage--or the otic vesicle is not induced at all--in all of the affected individuals who carried two mutant FGF3 alleles PMID: 17236138
    17. FGF3, FGF7, FGF10, FGF18, and FGFR1 may have roles in nonsyndromic cleft lip and palate PMID: 17360555
    18. Implication of FGF3 and FADD in human craniofacial disease. PMID: 17656375
    19. sequenced the FGF3 gene in 10 unrelated families in which probands had congenital deafness associated with various inner ear anomalies, including Michel aplasia, with or without tooth or external ear anomalies. PMID: 18435799
    20. study identified a homozygous missense mutation (c.196G-->T) in FGF3 in 21 affected individuals from a large extended family phenotypically characterized by autosomal recessive syndromic congenital sensorineural deafness, microtia and microdontia PMID: 18701883
    21. Loss of FGFR3 signaling provides evidence that extracellular signals regulate not simply the proliferation or survival of radial glial cells, but specifically their progression to intermediate progenitor cells during neurogenesis in vivo. PMID: 19923290

    顯示更多

    收起更多

  • 相關疾病:
    Deafness with labyrinthine aplasia, microtia and microdontia (LAMM)
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Heparin-binding growth factors family
  • 數據庫鏈接:

    HGNC: 3681

    OMIM: 164950

    KEGG: hsa:2248

    STRING: 9606.ENSP00000334122

    UniGene: Hs.37092



主站蜘蛛池模板: 亚洲日韩国产精品乱-久| 真人无码作爱免费视频| 忘忧草在线社区www中国中文| 妺妺窝人体色www婷婷| 蜜桃一区二区三区| 137裸交肉体摄影| 欧美成人天天综合在线| 亚洲成a人片在线观看中文无码| 大肉大捧一进一出好爽视色大师| 国语精品一区二区三区| 无码精品人妻一区二区三区人妻斩| 国产真实偷乱视频| 国产精品麻豆aⅴ人妻| 在线a久青草视频在线观看| 成年美女黄网站色大免费全看| 阳茎伸入女人阳道视频免费| 一二三四视频社区在线播放中国 | 亚洲日韩精品a∨片无码加勒比| 欧洲极品无码一区二区三区| 97熟女毛毛多熟妇人妻aⅴ| 日韩丰满少妇无码内射| 日日躁夜夜躁白天躁晚上| 黄网站色成年片在线观看| 色综合久久婷婷五月| 精品人妻少妇一区二区| 日韩毛片在线视频x| 国色天香天天影院综合网| a毛片免费全部播放自慰| 人人爽人人爽人人爽| 精品国精品无码自拍自在线| 国产激情无码视频在线播放| 少妇人妻挤奶水中文视频毛片 | 欧美两根一起进3p做受视频| 又爽又黄又无遮挡网站| 精品人无码一区二区三区| 一区二区三区在线 | 网站| 亚洲色欲天天天堂色欲网| 在线亚洲中文精品第1页| 在线观看老湿视频福利| 欧美gv在线观看| 九色精品国产成人综合网站|