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FGF16 Antibody, Biotin conjugated

  • 中文名稱:
    FGF16兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA008621LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FGF16 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FGF 16 antibody; FGF-16 antibody; Fgf16 antibody; FGF16_HUMAN antibody; Fibroblast growth factor 16 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fibroblast growth factor 16 protein (1-207AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
  • 基因功能參考文獻:
    1. Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID: 28409700
    2. Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID: 24878828
    3. impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID: 24706454
    4. Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID: 20097674
    5. HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID: 16756958

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  • 相關疾病:
    Metacarpal 4-5 fusion (MF4)
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Heparin-binding growth factors family
  • 數據庫鏈接:

    HGNC: 3672

    OMIM: 300827

    KEGG: hsa:8823

    STRING: 9606.ENSP00000399324

    UniGene: Hs.666364



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