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FGF11 Antibody

  • 中文名稱:
    FGF11兔多克隆抗體
  • 貨號:
    CSB-PA006109
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of NIH-3T3 Hela cells using FGF-11 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    FGF11
  • 別名:
    FGF 11 antibody; FGF-11 antibody; FGF11 antibody; FGF11_HUMAN antibody; FHF 3 antibody; FHF-3 antibody; FHF3 antibody; Fibroblast growth factor 11 antibody; Fibroblast growth factor homologous factor 3 antibody; FLJ16061 antibody; MGC102953 antibody; MGC45269 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human FGF-11.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probably involved in nervous system development and function.
  • 基因功能參考文獻:
    1. Endothelial miR-342-3p expression was significantly compromised in T2DM organisms and this inhibition powerfully blocked vasculogenesis in vivo by repressing endothelial proliferation and migration. From a mechanistic standpoint, miR-342-3p promoted the transactivation of fibroblast growth factor 11 (FGF11) by directly targeting its 3' untranslated regions (3'UTRs). PMID: 29852165
    2. FGF11 as a novel factor driving pathological bone resorption in osteolytic disease and as a potential target for the development of new anti-resorptive therapeutic agents PMID: 28097375
    3. Exosomal miR-24-3p is involved in tumour pathogenesis by mediating T-cell suppression via repression of FGF11, and may serve as a potential prognostic biomarker in nasopharyngeal carcinoma (NPC). PMID: 27538493
    4. these results suggest a cross-regulation between HIF-1alpha and FGF11, through which hypoxia-induced FGF11 reinforces hypoxia responses by enhancing the stability of HIF-1alpha. PMID: 28027390
    5. Study found that FGF11 expression can be induced through HIF-1 binding sites in its promoter region suggesting that FGF11 acts as a novel modulator of hypoxia-induced pathological processes such as tumor progression. PMID: 26323829
    6. these results concluded that infiltrating CD4(+) T cells could promote PCa metastasis via modulation of FGF11-->miRNA-541-->AR-->MMP9 signaling. PMID: 25135278

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  • 蛋白家族:
    Heparin-binding growth factors family
  • 組織特異性:
    Nervous system.
  • 數據庫鏈接:

    HGNC: 3667

    OMIM: 601514

    KEGG: hsa:2256

    STRING: 9606.ENSP00000293829

    UniGene: Hs.655193



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