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Your Good Partner in Biology Research

FETUB Antibody

  • 中文名稱:
    FETUB兔多克隆抗體
  • 貨號:
    CSB-PA008598GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    FETUB
  • 別名:
    16G2 antibody; 2310011O17Rik antibody; AI255764 antibody; D17980 antibody; Fet antibody; Fetub antibody; FETUB_HUMAN antibody; Fetuin beta antibody; Fetuin-B antibody; Fetuin-like protein antibody; Fetuin-like protein IRL685 antibody; Gugu antibody; IRL685 antibody; Pp63 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human fetuin-B
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening.
  • 基因功能參考文獻:
    1. High Serum fetuin-B expression is associated with insulin resistance. PMID: 29194974
    2. fetuin B may serve as a potential biomarker for coronary artery disease PMID: 28822077
    3. Increased serum fetuin-B level was significantly associated with higher risk of insulin resistance. Common genetic variants of FETUB SNPs (rs4686434, rs6785067, and rs3733159) were significantly associated with serum fetuin-B concentrations but were not associated with insulin resistance. PMID: 29390354
    4. serum level of fetuin B in the control subjects was lower than it in nonalcoholic fatty liver disease patients. fetuin B correlated with diastolic blood pressure, serum alanine transaminase and triglycerides, among the controls. It suggested a potential association between serum fetuin B and the presence of NAFLD. PMID: 27628583
    5. Further studies need to elucidate factors contributing to fetuin B regulation in humans, as well as the pathophysiological significance of fetuin B upregulation in gestational diabetes PMID: 28183456
    6. Data indicate that fetuin-B was one of the highly expressed serum proteins in acute myocardial infarction. PMID: 25671698
    7. Reduced expression of fetuin-b led to a significant increase in the expression of lipogenic genes, thereby resulting in higher lipid levels. PMID: 22739111
    8. serum fetuin has a role in processing and transport of matrix gamma-carboxyglutamic acid protein and bone morphogenetic protein-2 in cultured human vascular smooth muscle cells PMID: 15280384
    9. results support the hypothesis that fetuin-A serum levels are associated with bone cell activity PMID: 16797392

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  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Fetuin family
  • 組織特異性:
    Liver and testis.
  • 數據庫鏈接:

    HGNC: 3658

    OMIM: 605954

    KEGG: hsa:26998

    STRING: 9606.ENSP00000265029

    UniGene: Hs.81073



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