在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FCRL4 Antibody

  • 中文名稱:
    FCRL4兔多克隆抗體
  • 貨號:
    CSB-PA836277LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: FCRL4 antibody at 6µg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 58, 57 kDa
      Observed band size: 58 kDa
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) FCRL4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CD307d antibody; Fc receptor homolog 4 antibody; Fc receptor like 4 antibody; Fc receptor like protein 4 antibody; Fc receptor-like protein 4 antibody; FcR like protein 4 antibody; FcR-like protein 4 antibody; FcRH4 antibody; FcRL4 antibody; FCRL4_HUMAN antibody; hIFGP2 antibody; IFGP family protein 2 antibody; IGFP2 antibody; Immune receptor translocation associated protein 1 antibody; Immune receptor translocation-associated protein 1 antibody; Immunoglobulin superfamily receptor translocation associated 1 antibody; Immunoglobulin superfamily receptor translocation associated gene 1 antibody; IRTA1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Fc receptor-like protein 4 protein (20-387AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,F(xiàn)CRL4 Antibody (CSB-PA836277LA01HU),的標記方式是Non-conjugated。對于FCRL4 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA836277LB01HU FCRL4 Antibody, HRP conjugated ELISA
    FITC CSB-PA836277LC01HU FCRL4 Antibody, FITC conjugated
    Biotin CSB-PA836277LD01HU FCRL4 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    May function as an inhibitor of the B-cell receptor signaling. May function in the B-cell-mediated immune response.
  • 基因功能參考文獻:
    1. We conclude that these activated B cells are a component of the local autoimmune response, and through their RANKL expression, can contribute to joint destruction. Furthermore, their expression of FcRL4 and their enrichment in the IgA isotype points towards a potential role for these cells in the link between mucosal and joint inflammation. PMID: 28343748
    2. intraepithelial FcRL4(+) B-cells are present in the salivary glands of pSS patients. These cells are likely involved in the epithelial changes seen in pSS. Their enrichment in parotid glands may explain why MALT lymphomas in pSS patients preferentially develop at this specific location. PMID: 28390747
    3. Commercially available IRTA1 antibody can immunohistochemically distinguish MALT lymphoma from other low-grade B-cell lymphomas. PMID: 27666766
    4. Significantly increased FCRL4 mRNA only in Graves disease patients but not in Hashimoto patients compared to normal controls. PMID: 25738996
    5. The observed significant gene-environment interaction suggests that drinking and cooking oil use with FCRL4 gene polymorphism has a significant interaction. PMID: 25012527
    6. we provide evidence for involvement of HCK and FGR in FCRL4-mediated immunoregulation and for the functional importance of posttranslational modifications of the FCRL4 molecule. PMID: 25972488
    7. IRTA1 and T-bet are positive markers for the diagnosis of nodal marginal zone lymphoma PMID: 23855758
    8. Data indicate that signaling by HIV-1 gp120 through integrin alpha4beta7 resulted in increased expression of the immunosuppressive cytokine TGF-beta1 and FcRL4. PMID: 24162774
    9. The cytological features, growth pattern and IRTA1 positivity in nodal marginal zone lymphomas suggest they may derive from IRTA1(+) perifollicular B cells or monocytoid B cells detectable in reactive lymph nodes. PMID: 22716304
    10. The FCRL4 polymorphisms may play an important role in the susceptibility and severity of ankylosing spondylitis in the Chinese Han population. PMID: 22777505
    11. In cellular binding assays, as a bona fide receptor FcRL4 binds efficiently to immunoglobulin (Ig)A. PMID: 22491254
    12. Data suggest that expression of FcRL4 in B-cells results in inhibition of BCR signaling at point of Syk phosphorylation by mechanism that involves phosphorylation of FcRL4 and its association with SHP-1/SHP-2. PMID: 21908428
    13. role of IRTA1 in the immune function of B cells within epithelia PMID: 12881317
    14. Monocytoid B cells differ in their antigen profile (presence of IRTA1) from splenic and nodal marginal zone B cells. PMID: 16079106
    15. Cell surface expression of this immunoregulatory molecule is restricted to a subpopulation of memory B cells. PMID: 16157685
    16. Down-regulation of FCRL4 is associated with acute lymphoblastic leukemia. PMID: 18802695
    17. FCRL4 is located on atypical memory B cells population significantly expanded in Plasmodium falciparum-exposed Malian adults and children PMID: 19592645

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    A chromosomal aberration involving FCRL4 is found in non-Hodgkin lymphoma (NHG). Translocation t(1;1)(p36.3; q21.1-2).
  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Specifically expressed by memory and monocytoid B-cells which populate spleen and lymph nodes. Preferentially expressed in memory B-cells associated with mucosal tissue (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 18507

    OMIM: 605876

    KEGG: hsa:83417

    STRING: 9606.ENSP00000271532

    UniGene: Hs.120260



主站蜘蛛池模板: 新版天堂资源中文8在线| 亚洲中文字幕无码天然素人| 熟妇激情内射com| 麻豆成人精品国产免费| 4hu四虎永久在线观看| 在线亚洲日产一区二区| 无码人妻一区二区三区免费n鬼逝| 亚洲精品午夜国产va久久成人| 精品少妇人妻av一区二区| 中文字幕熟妇人妻在线视频| 在线精品视频一区二区三四| 中文有码无码人妻在线| 免费三级现频在线观看免费| 人人做人人爽国产视| 欧美性大战xxxxx久久久√| 天美麻花果冻视频大全英文版| 一本色道无码道dvd在线观看| 欧美亚洲人成网站在线观看| 久久99精品国产99久久6男男| av免费网址在线观看| 在线人人车操人人看视频| 国产亚洲精品国产福利你懂的| 欧美日韩国产精品| 狠狠色综合7777久夜色撩人 | 日本乱子伦一区二区三区| 日本高清www午色夜com | 97se亚洲国产综合自在线| 精品国产乱码一区二区三区| 无码av中文一区二区三区桃花岛| 久久久喷潮一区二区三区| 日韩欧美激情兽交| 精产国品一二三产区m553麻豆| 99re6热视频这里只精品首页| 日本高清不卡aⅴ免费网站| 女人被狂躁的高潮免费视频 | 欧美日韩无套内射另类| 国产午夜高清高清在线观看| 噜噜噜亚洲色成人网站∨| 久久精品女人天堂av麻| 宅宅午夜无码一区二区三区| 夜先锋av资源网站|