在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FCGR2C Antibody

  • 中文名稱:
    FCGR2C兔多克隆抗體
  • 貨號:
    CSB-PA008542ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: FCGR2C antibody IgG at 1.67μg/ml + Human Burkitt lymphoma cells
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 36, 31, 30, 26 kDa
      Observed band size: 36 kDa
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA008542ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA008542ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FCGR2C Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FCGR2C; CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-c; IgG Fc receptor II-c; CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD antigen CD32
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Low affinity immunoglobulin gamma Fc region receptor II-c protein (43-223AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
  • 基因功能參考文獻:
    1. When higher-affinity genotypes for FCGR2A, FCGR3A, and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 treatment PMID: 27742794
    2. The nonclassical open reading frame in the FCGR2C gene (FCGR2C.nc-ORF) was strongly associated with a decreased alloimmunization risk (odds ratio [OR] 0.26, 95% confidence [CI] 0.11-0.64). PMID: 28899854
    3. Gene copy number variation (CNV) of the PKLR, FCGR2A, FCGR2C, and FCGR3 genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria. PMID: 28605553
    4. FCGR2A and FCGR2C polymorphisms may also contribute to immunocomplexemia present in sarcoidosis. PMID: 26801149
    5. The findings of this study highlight further ethnic variation at the FCGR gene locus, in particular for FCGR2C, a gene with increasingly recognized clinical significance. PMID: 26673965
    6. FCGR2C SNPs that associated with vaccine efficacy in RV144 also strongly associated with the expression of FCGR2A/C and one of them also associated with the expression of Fc receptor-like A (FCRLA), another Fc-gamma receptor (FcgammaR) gene PMID: 27015273
    7. These include an FCGR2A/2C chimeric gene that causes a decreased expression PMID: 26133275
    8. Data show that gains or losses in copy numbers of Fc gamma receptors FCGR3A were less frequent than for FCGR3B and FCGR2C. PMID: 26032265
    9. sequenced exons and surrounding areas of FcR-encoding genes and found one FCGR2C tag SNP (rs114945036) that associated with vaccine efficacy against HIV-1 subtype CRF01_AE, with lysine at position 169 (169K) in the V2 loop (CRF01_AE 169K) PMID: 25105367
    10. We report the discovery of allele-dependent expression of the activating FcgammaRIIc on B cells. Identical to FcgammaRIIb in the extracellular domain, FcgammaRIIc has a tyrosine-based activation motif in its cytoplasmic domain. PMID: 24353158
    11. study concludes gene copy number of FcgammaR2C and FcgammaR3B influences IVIG treatment response and predisposes individuals to Kawasaki disease, providing potential insights into understanding the mechanism of the FcgammaR gene family in the IVIG pathway PMID: 23778324
    12. Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus.(28-40) Status: Complete Incomplete Delete PMID: 23261299
    13. Two additional variations in FcgammaRIIb/c expression on leukocytes have now been identified; findings demonstrate a more extensive and previously unnoticed variation in FcgammaR expression with relevance to immunity and inflammation. PMID: 22198951
    14. Fragment c gamma receptor gene polymorphisms is not associated with breast cancer. PMID: 20978933
    15. activating FCGR2C-ORF genotype predisposes to idiopathic thrombocytopenic purpura by altering the balance of activating and inhibitory FcgammaR on immune cells PMID: 17827395
    16. Only FCGR3A, FCGR2C and FCGR3B show copy number variation, in contrast to FCGR2A and FCGR2B. PMID: 19309690

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform IIC4]: Cytoplasm.; [Isoform IIC3]: Cell membrane; Single-pass type I membrane protein.; [Isoform IIC2]: Cell membrane; Single-pass type I membrane protein.; [Isoform IIC1]: Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells.
  • 數據庫鏈接:

    HGNC: 15626

    OMIM: 612169

    KEGG: hsa:9103

    UniGene: Hs.654395



主站蜘蛛池模板: 色777狠狠狠综合| 日韩人妻中文无码一区二区七区| 性欧美疯狂xxxxbbbb| 欧美国产精品久久久乱码| 老子影院午夜伦手机不四虎卡| 又色又爽又黄的视频网站| 欧美人与物videos另类xxxxx| 日本一区二区a√成人片| 高清国产在线拍揄自揄视频| 无码乱码av天堂一区二区| 老司机亚洲精品影院无码| 秋霞电影网午夜鲁丝片无码| 日本少妇寂寞少妇aaa| 偷偷色噜狠狠狠狠的777米奇| 丰满五十六十老熟女hd| 成人3d动漫一区二区三区| 免费国产在线精品一区不卡 | 国产成人精品av| 国外av无码精品国产精品| 精品人妻中文字幕有码在线| 亚洲人成无码网站18禁10| 青青草av国产精品| 国产精自产拍久久久久久蜜| 男女又色又爽又爽视频| 日韩a人毛片精品无人区乱码| 一本大道东京热无码| 国产69精品久久久久久久 | 一边吃奶一边做动态图| 亚洲日韩va无码中文字幕| 巨大乳做爰视频在线看| 香港三级日本三级韩级人妇| 久久99国产亚洲高清观看首页| 国产在线观看无码的免费网站| 国产午夜亚洲精品国产成人| 宝宝好涨水快流出来免费视频| 一本一本久久a久久精品综合| 五月色丁香婷婷网蜜臀av| 成人无码a∨电影免费| 久久人妻少妇嫩草av无码专区| 97无码免费人妻超级碰碰夜夜| 中国熟妇内谢69xxxxx|