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  4. FBXO44 Antibody

FBXO44 Antibody

  • 中文名稱：
    FBXO44兔多克隆抗體
  • 貨號：
    CSB-PA008509GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    FBXO44
  • 別名：
    5730411K09 antibody; AV001623 antibody; DKFZp781J0852 antibody; F box gene 3 antibody; F box only protein 44 antibody; F box only protein 6a antibody; F box protein 44 antibody; F box protein FBX30 antibody; F box/G domain protein 3 antibody; F-box only protein 44 antibody; F-box protein FBX30 antibody; F-box/G-domain protein 3 antibody; FBG3 antibody; FBX30 antibody; FBX44 antibody; FBX44_HUMAN antibody; FBX6A antibody; Fbxo44 antibody; Fbxo6a antibody; MGC14140 antibody; RGD1562463 antibody
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human FBXO44
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
  • 基因功能參考文獻：
    1. Although the overall structure of FBG3 is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3. PMID: 26460611
    2. FBXO44-mediated degradation of RGS2 protein uniquely depends on a Cul4B/DDB1 complex. PMID: 25970626
    3. FBXO44 mediates BRCA1 ubiquitination and degradation PMID: 23086937
    4. Skp1 and Fbg3 were co-expressed in E. coli. The plate-shaped crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 34.1, b = 76.6, c = 193.9 A and one molecule per asymmetric unit. PMID: 20057081
  • 組織特異性：
    Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver.
  • 數據庫鏈接：

    HGNC: 24847

    OMIM: 609111

    KEGG: hsa:93611

    STRING: 9606.ENSP00000251547

    UniGene: Hs.556006



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