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FARP2 Antibody

  • 中文名稱:
    FARP2兔多克隆抗體
  • 貨號:
    CSB-PA002536
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HuvEc cells using FIR Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FARP2 antibody; FARP2_HUMAN antibody; FERM antibody; FERM domain including RhoGEF antibody; FERM; RhoGEF and pleckstrin domain protein 2 antibody; FERM; RhoGEF and pleckstrin domain-containing protein 2 antibody; FGD1 related Cdc42 GEF antibody; FIR antibody; FRG antibody; KIAA0793 antibody; PH domain-containing family C member 3 antibody; Pleckstrin homology domain-containing family C member 3 antibody; PLEKHC3 antibody; RhoGEF and pleckstrin domain protein 2 antibody; RhoGEF and pleckstrin domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human FIR.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
  • 基因功能參考文獻:
    1. FRG is a member of Cdc42-GEF and plays an important role in the signaling pathway downstream of G protein-coupled receptors PMID: 12771149
  • 數據庫鏈接:

    HGNC: 16460

    OMIM: 617586

    KEGG: hsa:9855

    STRING: 9606.ENSP00000264042

    UniGene: Hs.726316



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