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  4. FAR1 Antibody, Biotin conjugated

FAR1 Antibody, Biotin conjugated

  • 中文名稱：
    FAR1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA837860LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) FAR1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FAR1
  • 別名：
    FAR1; MLSTD2; UNQ2423/PRO4981; Fatty acyl-CoA reductase 1; Male sterility domain-containing protein 2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Fatty acyl-CoA reductase 1 protein (182-343AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols. In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis.
  • 基因功能參考文獻：
    1. A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. PMID: 25439727
    2. Expression of Far1 increased plasmalogen synthesis in wild-type Chinese hamster ovary cells, strongly suggesting that Far1 is a rate-limiting enzyme for plasmalogen synthesis. PMID: 24108123
    3. ether lipid biosynthesis in mammalian cells is regulated by a negative feedback mechanism that senses cellular plasmalogen levels and appropriately increases or decreases Far1 PMID: 20071337
  • 相關(guān)疾病：
    Peroxisomal fatty acyl-CoA reductase 1 disorder (PFCRD)
  • 亞細胞定位：
    Peroxisome membrane; Single-pass membrane protein.
  • 蛋白家族：
    Fatty acyl-CoA reductase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 26222

    OMIM: 616107

    KEGG: hsa:84188

    STRING: 9606.ENSP00000346874

    UniGene: Hs.501991



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