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FAM49B Antibody

  • 中文名稱:
    FAM49B兔多克隆抗體
  • 貨號:
    CSB-PA873658LA01HU
  • 規格:
    ¥440
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FAM49B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FAM49B
  • 別名:
    BM 009 antibody; FA49B_HUMAN antibody; Fam49b antibody; Family with sequence similarity 49; member B antibody; L1 antibody; Protein FAM49B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein FAM49B protein (1-324AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,FAM49B Antibody (CSB-PA873658LA01HU),的標記方式是Non-conjugated。對于FAM49B Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA873658LB01HU FAM49B Antibody, HRP conjugated ELISA
    FITC CSB-PA873658LC01HU FAM49B Antibody, FITC conjugated
    Biotin CSB-PA873658LD01HU FAM49B Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling. Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization. Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry. Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes. Involved in the regulation of mitochondrial dynamics and oxidative stress.
  • 基因功能參考文獻:
    1. FAM49B inhibits T cell activation by repressing Rac activity and modulating cytoskeleton reorganization. PMID: 29632189
    2. Three proteins-matrix metalloproteinase-9, neutrophil elastase, and FAM49B-were significantly lower in abundance in samples from women with endometriosis. PMID: 25284053
    3. FAM49B is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
  • 亞細胞定位:
    Membrane; Lipid-anchor. Mitochondrion.
  • 蛋白家族:
    FAM49 family
  • 數據庫鏈接:

    HGNC: 25216

    KEGG: hsa:51571

    STRING: 9606.ENSP00000384880

    UniGene: Hs.126941



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