在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FAM20A Antibody

  • 中文名稱:
    FAM20A兔多克隆抗體
  • 貨號:
    CSB-PA850394ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA850394ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA850394ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) FAM20A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FAM20A
  • 別名:
    FAM20A antibody; UNQ9388/PRO34279Pseudokinase FAM20A antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Pseudokinase FAM20A protein (140-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.
  • 基因功能參考文獻:
    1. three patients with homozygous or compound heterozygous mutations in FAM20A and findings that extend the phenotypic spectrum of this disorder, showing that protein truncation is associated with greater clinical severity. PMID: 28298625
    2. Fam20A potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro. PMID: 25789606
    3. our findings support the suggestion that enamel-renal and AIGFSs are actually the same entity with different manifestations, associated with FAM20A mutations. PMID: 24259279
    4. the first duplication in FAM20A and the fifth independent mutation associated with gingival hyperplasia and dental anomalies, is reported. PMID: 23697977
    5. study identified 3 novel FAM20A mutations that caused autosomal-recessive amelogenesis imperfecta with delayed and arrested tooth eruption; conclude that FAM20A is likely a secretory pathway kinase and that loss-of-function mutations cause pathology where its phosphorylations are necessary for normal development or homeostasis PMID: 24196488
    6. Data indicate that autosomal recessive FAM20A mutations causes nephrocalcinosis and amelogenesis imperfecta. PMID: 23434854
    7. we conclude that FAM20A, which has a kinase homology domain and localizes to the Golgi, is a putative Golgi kinase that plays a significant role in the regulation of biomineralization processes. PMID: 23468644
    8. Myocardial infarction is distinguished by the up-regulation of SOCS3 and FAM20A genes within first days in the vast majority of patients. PMID: 23185530
    9. Three homozygous mutations in three families, and a compound heterozygous mutation in one family with hypoplastic amelogenesis imperfecta have been identified in FAM20A. PMID: 21990045
    10. We identified a homozygous nonsense mutation in exon 2 of FAM20A that was not present in the Single Nucleotide Polymorphism database (dbSNP), the 1000 Genomes database, or the Centre d'Etude du Polymorphisme Humain (CEPH) Diversity Panel. PMID: 21549343
    11. A homozygous nonsense mutation in exon 2 of FAM20A underlies Amelogenesis imperfecta (AI) -- disorders of biomineralization resulting from failure of normal enamel formation. PMID: 21549343

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Amelogenesis imperfecta 1G (AI1G)
  • 亞細胞定位:
    Secreted. Golgi apparatus. Endoplasmic reticulum.
  • 蛋白家族:
    FAM20 family
  • 組織特異性:
    Highly expressed in lung and liver. Intermediate levels in thymus and ovary.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 23015

    OMIM: 204690

    KEGG: hsa:54757

    STRING: 9606.ENSP00000468308

    UniGene: Hs.268874



主站蜘蛛池模板: 窝窝午夜色视频国产精品破| 欧洲精品无码一区二区三区在线播放 | 日本道色综合久久影院| 日本在线a一区视频| 亚洲免费视频免在线观看| 中国丰满人妻videoshd| 少妇无码一区二区二三区| 婷婷色爱区综合五月激情| 欧美天天拍在线视频| 国产色爱av资源综合区| 最近在线更新8中文字幕免费| 亚洲欧美日韩中字视频三区| 成人免费乱码大片a毛片| 免费观看黄网站在线播放| 日本高清视频www夜色资源| 久久亚洲国产精品影院| 精品一区国产vr| 久久午夜无码鲁丝片午夜精品| 少妇高清精品毛片在线视频| 一本色道久久东京热| 国产高清在线精品二区| 国产激情久久久久久熟女老人av | 无套内谢孕妇毛片免费看看| 国模裸体无码xxxx视频| 久久精品香蕉绿巨人登场| 国产一区二区三区免费高清在线播放 | 成 人 a v免费视频在线观看 | 校园春色~综合网| 精品久久久久久中文墓无码| av制服丝袜白丝国产网站| 亚洲啪av永久无码精品放毛片| 久久综合九色综合97网| 国产午夜不卡片免费视频| 国产成人免费永久在线平台| 性大毛片视频| 青乐娱精品视频一国产分类| 欧美真人做爰在线观看| 亚洲伊人色欲综合网| 丰满少妇大叫太大太粗| 国产精品久久久久蜜芽| 久久亚洲私人国产精品|