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FAM120A Antibody

  • 中文名稱:
    FAM120A兔多克隆抗體
  • 貨號(hào):
    CSB-PA008027GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    FAM120A
  • 別名:
    C9orf10 antibody; Chromosome 9 open reading frame 10 antibody; Constitutive coactivator of PPAR gamma like protein 1 antibody; Constitutive coactivator of PPAR-gamma-like protein 1 antibody; DNA polymerase transactivated protein 5 antibody; DNA polymerase transactivated protein 1 antibody; DNAPTP1 antibody; DNAPTP5 antibody; F120A_HUMAN antibody; FAM120A antibody; Family with sequence similarity 120A antibody; Hypothetical protein LOC23196 antibody; KIAA0183 antibody; LOC23196 antibody; MGC111527 antibody; MGC133257 antibody; OSSA antibody; Oxidative stress-associated Src activator antibody; Protein FAM120A antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human FAM120A
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May participate in mRNA transport in the cytoplasm. Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
  • 基因功能參考文獻(xiàn):
    1. his study shows that widespread structural brain involvement is not limited to C9+ patients, but also presents in a subgroup of C9- patients with ALS and relates to cognitive deficits. Our neuroimaging findings reveal an intermediate phenotype that may provide insight into the complex relationship between genetic factors and clinical characteristics. PMID: 27756805
    2. Results identify novel SNP in FAM120A on chromosome 9 associated with differences in BMI in childhood which may predispose obesity. PMID: 25953783
    3. Results identified FAM120A in the IL13/IL13Ralpha2 signaling pathway as a key mediator of invasion and liver metastasis in colon cancer. PMID: 25896327
    4. study reports that C9orf10 (designated Ossa for oxidative stress-associated Src activator) is a novel RNA-binding protein that guards cancer cells from oxidative stress-induced apoptosis by activation of Src family kinases PMID: 19015244
  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates to plasma membrane upon ultraviolet exposure.
  • 蛋白家族:
    Constitutive coactivator of PPAR-gamma family
  • 組織特異性:
    Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 13247

    OMIM: 612265

    KEGG: hsa:23196

    STRING: 9606.ENSP00000277165

    UniGene: Hs.372003



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