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  4. EXPH5 Antibody, FITC conjugated

EXPH5 Antibody, FITC conjugated

  • 中文名稱：
    EXPH5兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA843342LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EXPH5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EXPH5
  • 別名：
    EXPH5 antibody; KIAA0624 antibody; SLAC2BExophilin-5 antibody; Synaptotagmin-like protein homolog lacking C2 domains b antibody; SlaC2-b antibody; Slp homolog lacking C2 domains b antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Exophilin-5 protein (1235-1490AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May act as Rab effector protein and play a role in vesicle trafficking.
  • 基因功能參考文獻：
    1. Mutations in EXPH5 protein, human have been implicated in the physiopathology of Epidermolysis bullosa simplex. PMID: 27384765
    2. The results identify a further EXPH5 pedigree suggest that mutations in EXPH5 should be considered as a possible candidate gene for recessive or sporadic cases of mild generalized EBS. PMID: 26211931
    3. Here, we report the second family with two EXPH5 mutations in epidermolysis bullosa simplex. PMID: 24005056
    4. our findings identify an unexpected role for Slac2-b in inherited skin fragility and expand the clinical spectrum of human disorders of GTPase effector proteins. PMID: 23176819
    5. Slac2-b/KIAA0624 contains an N-terminal Slp homology domain (SHD) (PMID: 11327731). The SHD of Slac2-b specifically and directly binds the GTP-bound form of Rab27A (J. Biol. Chem. 277, (2002) 9212-9218; PMID: 11773082). PMID: 11773082

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  • 相關疾病：
    Epidermolysis bullosa, non-specific, autosomal recessive (EBNS)
  • 組織特異性：
    Expressed in keratinocytes.
  • 數據庫鏈接：

    HGNC: 30578

    OMIM: 612878

    KEGG: hsa:23086

    STRING: 9606.ENSP00000265843

    UniGene: Hs.28540



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