在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EXOC4 Antibody

  • 中文名稱:
    EXOC4兔多克隆抗體
  • 貨號:
    CSB-PA007882GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    EXOC4
  • 別名:
    dSec8 antibody; EXOC 4 antibody; Exoc4 antibody; EXOC4_HUMAN antibody; Exocyst complex component 4 antibody; Exocyst complex component SEC8 antibody; KIAA1699 antibody; MGC27170 antibody; REC 8 antibody; REC8 antibody; rSec 8 antibody; Sec 8 antibody; Sec 8p antibody; Sec8 antibody; SEC8 like 1 antibody; SEC8 protein antibody; Sec8L1 antibody; Sec8p antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human EXOC4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
  • 基因功能參考文獻:
    1. Sec8 regulates N-cadherin expression by controlling Smad3 and Smad4 expression through CBP, thereby mediating the epithelial-mesenchymal transition. PMID: 27769780
    2. Sec8 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. PMID: 26892009
    3. Sec8 regulates histone-modifying proteins ATF2 and RNF20. PMID: 26283729
    4. Sec8 knockdown in HSC3 cells resulted in reduced expressions of PAK1 and PAK2 by upregulating Pirh2 and Siah1 expression, which inhibited the ERK or p38 MAPK signalling pathway and cytokeratin8 phosphorylation and cell migration. PMID: 25725287
    5. knockdown of Sec8 enhances the binding of JIP4 to MAPK kinase 4, thereby decreasing the phosphorylation of MAPK kinase 4, JNK, and p38. PMID: 25244576
    6. Exome sequencing revealed a likely pathogenic mutation in three novel candidate MKS disease genes-C5orf42, EVC2 and SEC8 (also known as EXOC4), which encodes an exocyst protein with an established role in ciliogenesis PMID: 23169490
    7. High Sec8 expression is associated with progression of oral squamous-cell carcinoma by secretion of matrix metalloproteinases. PMID: 23207790
    8. EXOC4 is involved in insulin-stimulated glucose transport and may be a candidate for an association with type 2 diabetes. PMID: 18498660

    顯示更多

    收起更多

  • 亞細胞定位:
    Midbody, Midbody ring. Cell projection.
  • 蛋白家族:
    SEC8 family
  • 數據庫鏈接:

    HGNC: 30389

    OMIM: 608185

    KEGG: hsa:60412

    STRING: 9606.ENSP00000253861

    UniGene: Hs.321273



主站蜘蛛池模板: 在线播放人成视频观看| 香蕉久久国产av一区二区| 国产香蕉97碰碰久久人人| 在线永久免费观看黄网站| 少妇无码一区二区三区| 国产乱子伦三级在线播放| 久久人人超碰精品caoporen| 宝贝腿开大点我添添公视频免费| 免费无码一区二区三区a片百度| 欧美精品videosex性欧美| 欧美成人一区二区三区| 中国性欧美videofree精品| 久久精品中文字幕有码| 久青青视频在线观看久| 国产亚洲精品美女久久久久| 法国啄木乌av片在线播放| 日本中文字幕人妻不卡dvd| 午夜131美女爱做视频| 男女免费观看在线爽爽爽视频| 亚洲中文字幕无码永久在线| 久久精品国产99国产精品导航| 国产人妻高清国产拍精品| 国产午夜精华2020在线| 产后漂亮奶水人妻无码| 无码毛片内射白浆视频| 无码人妻一区二区三区免费| 欧美亚洲人成网站在线观看 | 久久久99精品成人片| 国产乱人伦真实精品视频| 国产免费艾彩sm调教视频 | 亚洲欧洲无码av电影在线观看| 无码人妻久久一区二区三区app| 久久九九久精品国产免费直播| 巨大黑人极品videos精品| 亚洲欧美色αv在线影视| 久久人人爽av亚洲精品| 国产视频一区二区| 日日碰狠狠躁久久躁蜜桃 | 特黄大片又粗又大又暴| 精品国产久九九| 国产午夜理论不卡在线观看|