在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ETV5 Antibody, HRP conjugated

  • 中文名稱:
    ETV5兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA007859LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ETV5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ETV5
  • 別名:
    ERM antibody; Ets related protein ERM antibody; ETS translocation variant 5 antibody; Ets variant gene 5 antibody; Ets-related protein ERM antibody; ETV5 antibody; ETV5_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human ETS translocation variant 5 protein (124-265AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.
  • 基因功能參考文獻:
    1. exploration of the underlying mechanism demonstrated that ICAM3 not only binds to LFA-1 with its extracellular domain and structure protein ERM but also to lamellipodia with its intracellular domain which causes a tension that pulls cells apart (metastasis). PMID: 29729315
    2. High Etv5 expression is associated with glioma. PMID: 29787563
    3. Novel ETV5 SNP rs7647305 is associated with childhood hypertension adjusted by obesity. PMID: 28645872
    4. MiR-200b inhibition by transfection in MCF-7 markedly decreased miR-200b level, elevated ERM expression, and enhanced cell migration and invasion. MiR-200b overexpression in MDA-MB-231 obviously increased miR-200b level, reduced ERM expression, and weakened cell migration and invasion. PMID: 27276064
    5. Resistin, a fat-derived secretory factor, promotes metastasis of MDA-MB-231 human breast cancer cells through ERM activation PMID: 26729407
    6. ERM proteins contribute toward accelerated CD44 shedding by MT1-MMP through ERM protein-mediated interactions between their cytoplasmic tails. PMID: 26289026
    7. Our results reveal a novel ERM-based spatial mechanism that is coopted by DLBCL cells to sustain tumor cell growth and survival. PMID: 25801911
    8. Increase of ETV5 protein expression is associated with endometrial cancer invasion. PMID: 25924802
    9. Snail regulates the motility and invasiveness of oral cancer cells via RhoA/Cdc42/p-ERM pathway. PMID: 25172658
    10. there is a higher expression of ERM/ETV5 in early stages of endometrioid endometrial carcinomas PMID: 24756106
    11. we found that the downregulation of ETV5 reduced the expression of the oncogenic transcription factor FOXM1. PMID: 22589409
    12. This data suggests that ETV5 has a significant role in regulating MMP2 expression and therefore matrix resorption in human chondrosarcoma, and thus may be a targetable upstream effector of the metastatic cascade in this cancer. PMID: 22968857
    13. we propose ETV5-transcriptional regulation of the EMT process through a crosstalk with the tumor surrounding microenvironment, as a principal event initiating EC invasion. PMID: 22266854
    14. The homozygous +48845 G>T (TT allele) variant confers a higher risk for male infertility associated with nonobstructive azoospermia and Sertoli cell only syndrome in Australian men. PMID: 22771031
    15. Upregulation of ETV5 induced the expression of cell adhesion molecules and enhanced cell survival in a spheroid model. PMID: 21520040
    16. results indicate concurrent mechanisms in expression of MMP-2 and -9, RUNX1/AML1 and ETV5/ERM, and several basement membrane components, which likely associate with the invasive stage of endometrioid endometrial and ovarian endometrioid carcinoma. PMID: 20970160
    17. The flexible nature of transactivation domain may be instrumental for ERM recognition and binding to diverse molecular partners. PMID: 20647002
    18. functional role for the ERMs (ezrin/radixin/moesin) as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases PMID: 12387735
    19. ERM has a role in progression of breast cancer PMID: 15534105
    20. The erm gene expression is regulated by the conventional PKC (cPKC) pathway. PMID: 15620692
    21. CD44-mediated hyaluronan binding in myeloid cells is regulated by phosphorylated ERM and the actin cytoskeleton. PMID: 15652352
    22. ERM is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity PMID: 15857832
    23. Erm is involved in SP-C regulation, which results from an interaction with TTF-1 PMID: 16613858
    24. analysis of NHERF recognition by ERM proteins PMID: 16615918
    25. Testing various shorter fragments of ERM as bait indicated that the region essential for binding CHD3/ZFH is within the amino acid region 96-349, which contains the central inhibitory DNA-binding domain (CIDD) of ERM PMID: 17489097
    26. ERM/ETV5 up-regulation activates MMP-2 and thus has a role during myometrial infiltration in endometrial cancer PMID: 17638886
    27. A TMPRSS2:ETV5 gene fusion was identified in prostate cancer. PMID: 18172298

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    ETS family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 3494

    OMIM: 601600

    KEGG: hsa:2119

    STRING: 9606.ENSP00000306894

    UniGene: Hs.43697



主站蜘蛛池模板: 亚洲午夜精品a片久久www慈禧| 亚洲精品卡2卡3卡4卡5卡区| 国产日产欧洲无码视频| 国产在线观看无码的免费网站 | 国产精品不卡无码av在线播放 | 欧美18videosex性欧美黑吊| 国产露脸150部国语对白| 内射老妇bbwx0c0ck| 日本免费人成视频播放| 2021国产精品视频网站| 亚洲春色av无码专区在线播放| 97精品尹人久久大香线蕉| 国精产品一区一区三区免费视频 | 免费观看又色又爽又黄的崩锅| 午夜福利片手机在线播放| 狠狠色噜噜狠狠狠8888在| 国产精品无码翘臀在线看| 国产乱人伦精品一区二区在线观看| 51国偷自产一区二区三区| 亚洲欧美日韩国产手机在线| 亚洲国产精品久久久久婷婷软件| 亚洲国产精品无码久久久蜜芽| 小13箩利洗澡无码视频网站| 国产亚洲成av人片在线观黄桃| 国产午夜伦鲁鲁| 性强烈的欧美三级视频| 人人妻碰人人免费| 亚洲人成无码网www| 亚洲国产精品热久久| 亚洲国产日韩欧美一区二区三区| 国产av区男人的天堂| 特级a欧美做爰片第一次| 中文字幕有码无码人妻av蜜桃| 国产亚洲精品久久久网站好莱| 久久香港三级台湾三级播放| 男女做爽爽爽视频免费软件| 日本肉体裸xxxxbbbb| 国产精品成人av片免费看| 人人妻人人澡人人爽欧美一区九九| 成年网站未满十八禁视频天堂| 日本久久久久久级做爰片|