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  4. ESD Antibody

ESD Antibody

  • 中文名稱：
    ESD兔多克隆抗體
  • 貨號：
    CSB-PA007823GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ESD
  • 別名：
    EC 3.1.2.12 antibody; Es-10 antibody; Es10 antibody; ESD antibody; ESTD_HUMAN antibody; Esterase 10 antibody; Esterase D antibody; Esterase D formylglutathione hydrolase antibody; FGH antibody; FGH, included antibody; FLJ11763 antibody; Methylumbelliferyl acetate deacetylase antibody; MGC139609 antibody; OTTHUMP00000018374 antibody; OTTHUMP00000040929 antibody; S formylglutathione hydrolase antibody; S-formylglutathione hydrolase antibody; S-formylglutathione hydrolase, included antibody; Sid 478 antibody; sid478 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ESD
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Serine hydrolase involved in the detoxification of formaldehyde.
  • 基因功能參考文獻：
    1. rs7996797 located on chr13q14.1-q14.2 near the ESD gene was the most significantly associated with hallux valgus in females in genome-wide association meta-analyses. PMID: 26337638
    2. Abhydrolase domain-containing protein 11 and Esterase D predict the development of distant metastases and the presence of aggressive lung adenocarcinomas. PMID: 21596165
    3. The analysis involved the data on nine polymorphic codominant loci: HP, GC, TF, PI, PGM1, GLO1, C3, ACP1, and ESD. The loci were selected by significance of differences in genotype frequencies between tuberculosis patients and healthy controls PMID: 12942785
    4. Autoantibodies to EsteD and BB-CK produced in experimental autoimmune uveoretinitis -induced mice were also detected in some endogenous uveitis patients, suggesting that these proteins might be autoantigens. PMID: 18552983
    5. catalytic triad residues--Ser-153, His264, and Asp230--involved in catalysis. Mutagenesis of any of the catalytic triad residues to alanine abolished the enzyme activity. Backbone amides of Leu54 & Met150 are involved in the formation of the oxyanion hole PMID: 19126594

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  • 亞細胞定位：
    Cytoplasm. Cytoplasmic vesicle.
  • 蛋白家族：
    Esterase D family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3465

    OMIM: 133280

    KEGG: hsa:2098

    STRING: 9606.ENSP00000367992

    UniGene: Hs.432491



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