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  4. ESAM Antibody

ESAM Antibody

  • 中文名稱：
    ESAM兔多克隆抗體
  • 貨號：
    CSB-PA007818GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    2310008D05Rik antibody; Endothelial cell adhesion molecule antibody; Endothelial cell selective adhesion molecule antibody; Endothelial cell-selective adhesion molecule antibody; Esam antibody; ESAM_HUMAN antibody; HUEL (C4orf1) interacting protein antibody; LP4791 protein antibody; W117m antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ESAM
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Can mediate aggregation most likely through a homophilic molecular interaction.
  • 基因功能參考文獻：
    1. sESAM levels associate with myocardial infarction, heart failure, and death after adjustment for demographic and clinical risk factors, but not after adjustment for kidney function. PMID: 26523992
    2. ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias PMID: 26774386
    3. Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress. PMID: 24456423
    4. sESAM is associated with albuminuria and reduced kidney function in patients with coronary artery disease in both cross-sectional and longitudinal analyses. PMID: 24177327
    5. ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules. PMID: 20153339
    6. sESAM is a predictive biomarker and potential mediator of atherosclerosis. PMID: 19759376

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  • 亞細胞定位：
    Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Highly expressed in endothelial cells.
  • 數據庫鏈接：

    HGNC: 17474

    OMIM: 614281

    KEGG: hsa:90952

    STRING: 9606.ENSP00000278927

    UniGene: Hs.173840



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