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  4. ERP27 Antibody, FITC conjugated

ERP27 Antibody, FITC conjugated

  • 中文名稱：
    ERP27兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA842657LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ERP27 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ERP27
  • 別名：
    C12orf46 antibody; Chromosome 12 open reading frame 46 antibody; Endoplasmic reticulum protein 27 antibody; Endoplasmic reticulum protein 27 kDa antibody; Endoplasmic reticulum resident protein 27 antibody; Endoplasmic reticulum resident protein ERp27 antibody; ER protein 27 antibody; ERp 27 antibody; ERp27 antibody; ERP27_HUMAN antibody; FLJ32115 antibody; PDIA8 antibody; Protein disulfide isomerase family A; member 8 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Endoplasmic reticulum resident protein 27 protein (26-273AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Specifically binds unfolded proteins and may recruit protein disulfide isomerase PDIA3 to unfolded substrates. Binds protein substrates via a hydrophobic pocket in the C-terminal domain. May play a role in the unfolded stress response.
  • 基因功能參考文獻：
    1. High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility PMID: 23234573
    2. ERp27 is able to distinguish between folded and unfolded substrates, only interacting with the latter and presenting them to for catalysis. PMID: 23192347
    3. ERp27 is bound by ERp57 both in vitro and in vivo by a similar mechanism by which ERp57 binds calreticulin PMID: 16940051
  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Protein disulfide isomerase family
  • 數據庫鏈接：

    HGNC: 26495

    OMIM: 610642

    KEGG: hsa:121506

    STRING: 9606.ENSP00000266397

    UniGene: Hs.162143



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