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EPPK1 Antibody, Biotin conjugated

  • 中文名稱:
    EPPK1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA007745LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EPPK1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EPPK1
  • 別名:
    450 kDa epidermal antigen antibody; Epidermal autoantigen 450K antibody; EPIPL antibody; EPIPL_HUMAN antibody; EPIPL1 antibody; Epiplakin antibody; EPPK1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Epiplakin protein (1-225AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cytoskeletal linker protein that connects to intermediate filaments and controls their reorganization in response to stress. In response to mechanical stress like wound healing, is associated with the machinery for cellular motility by slowing down keratinocyte migration and proliferation and accelerating keratin bundling in proliferating keratinocytes thus contributing to tissue architecture. However in wound healing in corneal epithelium also positively regulates cell differentiation and proliferation and negatively regulates migration thereby controlling corneal epithelium morphogenesis and integrity. In response to cellular stress, plays a role in keratin filament reorganization, probably by protecting keratin filaments against disruption. During liver and pancreas injuries, plays a protective role by chaperoning disease-induced intermediate filament reorganization.
  • 基因功能參考文獻:
    1. Epiplakin may be a cytolinker involved in maintaining the integrity of intermediate filaments networks in simple epithelial cells. PMID: 15671067
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cell junction, hemidesmosome. Cell junction, tight junction. Cell projection. Apicolateral cell membrane. Basolateral cell membrane. Cell junction.
  • 蛋白家族:
    Plakin or cytolinker family
  • 組織特異性:
    Expressed in epithelial cells of liver, small intestine, colon, salivary glands, stomach and appendix.
  • 數據庫鏈接:

    HGNC: 15577

    OMIM: 607553

    KEGG: hsa:83481

    STRING: 9606.ENSP00000436337

    UniGene: Hs.200412



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