在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ENTPD2 Antibody

  • 中文名稱:
    ENTPD2兔多克隆抗體
  • 貨號:
    CSB-PA007691ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: ENTPD2antibody at 3.6μg/ml
      Lane 1: Human placenta tissue
      Lane 2: U87 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 54, 52, 49 kDa
      Observed band size: 54 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA007691ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA007691ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ENTPD2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ENTPD2
  • 別名:
    NTPDase 2 antibody; NTPDase2 antibody; CD39 antigen like 1 antibody; CD39 antigen-like 1 antibody; CD39 like1 antibody; CD39L1 antibody; CD39like1 antibody; ecto ATP diphosphohydrolase 2 antibody; ecto ATPase 2 antibody; ecto ATPDase 2 antibody; Ecto-ATP diphosphohydrolase 2 antibody; Ecto-ATPase 2 antibody; Ecto-ATPDase 2 antibody; ectoATPase 2 antibody; ectoATPDase 2 antibody; Ectonucleoside triphosphate diphosphohydrolase 2 antibody; ENTP2_HUMAN antibody; Entpd2 antibody; NTPDase 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 2 protein (28-268AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
  • 基因功能參考文獻:
    1. In oviducts, remarkably, ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase2), with the ability to hydrolyze ATP to AMP, are expressed in ciliated epithelial cells but with different subcellular localization. PMID: 29273916
    2. Hypoxia upregulates ENTPD2 through HIF-1alpha in hepatocellular carcinoma and subsequently leading to the accumulation of extracellular 5'-AMP, which maintains myeloid-derived suppressor cells undifferentiated. PMID: 28894087
    3. NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease. PMID: 28472257
    4. the lack of ecto-nucleotidase activity exhibited by NTPDase2 beta and -2 gamma and the C399S mutant, as well as the large reduction of activity in the N443D mutant are due to alterations in the folding/maturation of these proteins PMID: 12888562
    5. NTPDase2 preferentially hydrolyzes nucleoside triphosphates. PMID: 15496502
    6. down-regulation in biliary cirrhosis PMID: 15651265
    7. NTPDase2 has a role in portal fibroblast regulation of bile duct epithelium proliferation PMID: 15799977
    8. Mutagenesis study indicate the importance of K62 located in CR1, K182 downstream of ACR3, and R155. Mutation of Asp at the six potential glycosylation sites showed the importance of N64 in CR1 and N443 in ACR5 in protein function and expression PMID: 17489562
    9. The role of cysteine 26 in the catalytic activity of NTPDase-2 and as the target of p-chloromercuriphenylsulfonate (pCMPS), a sulfhydryl reagent and NTPDase-2 inhibitor, is reported. PMID: 18656957

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform Long]: Cell membrane; Multi-pass membrane protein.; [Isoform Short]: Endoplasmic reticulum membrane; Multi-pass membrane protein.; [Isoform gamma]: Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    GDA1/CD39 NTPase family
  • 組織特異性:
    Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 3364

    OMIM: 602012

    KEGG: hsa:954

    STRING: 9606.ENSP00000347213

    UniGene: Hs.123036



主站蜘蛛池模板: 亚洲国产婷婷综合在线精品| 国产av综合影院| 在线欧美日韩制服国产| 亚洲欧美日韩中文字幕在线一区| 欧美最猛性xxxxx大叫| 亚洲精品无码少妇30p| 色一情一乱一乱一区99av白浆| 女人被黑人狂躁c到高潮小说 | 国产熟女高潮视频| 亚洲精品国产一区二区精华液| 欧美性开放情侣网站| 精品午夜福利在线视在亚洲| 国产一卡2卡3卡四卡精品app| 九九re6热在线视频精品66| 午夜不卡久久精品无码免费| 亚洲熟妇色xxxxx亚洲| 亚洲免费综合色在线视频| 亚洲另类色区欧美日韩图片| 国产成人午夜精华液 | 在线播放国产精品三级网| 国产免费人成视频在线播放播| 国产国产裸模裸模私拍视频| 东京热人妻中文无码av| 人禽无码视频在线观看| 真人做人60分钟啪啪免费看| 羞涩的丰满人妻40p| 国产成人无码a区在线观看视频| 韩国美女视频黄是免费| 国产精品视频一区二区三区无码| 国产人妻xxxx精品hd| 亚洲 日本 欧美 中文幕| 精品久久久久久国产| 国内大量揄拍人妻在线视频| 久久亚洲日韩av一区二区三区| 激情按摩系列片aaaa| 中文字幕一区二区人妻| 日日躁夜夜躁狠狠躁超碰97| 一二三四在线视频观看社区| 国产又色又爽又黄的免费| 57pao成人国产永久免费视频| 国产成人无码a区在线|