ENPP4 Antibody

說明書

產品詳情

Uniprot No.：

Q9Y6X5
基因名：

ENPP4
別名：

KIAA0879 antibody; 4933413N07Rik antibody; AA986363 antibody; AI195364 antibody; E-NPP 4 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 antibody; ENPP4 antibody; ENPP4_HUMAN antibody; Gm90 antibody; mKIAA0879 antibody; NPP-4 antibody; NPP4 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human ENPP4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
基因功能參考文獻：
1. The combined studies expand our understanding of NPP1 and NPP4 substrate specificity and range and provide a rational mechanism by which polymorphisms in NPP1 confer stroke resistance. PMID: 24338010
2. NPP4 promotes hemostasis in vivo by augmenting ADP-mediated platelet aggregation at the site of vascular injury. PMID: 22995898
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
蛋白家族：

Nucleotide pyrophosphatase/phosphodiesterase family
組織特異性：

Expressed on the surface of vascular endothelia.
數據庫鏈接：

HGNC: 3359

OMIM: 617000

KEGG: hsa:22875

STRING: 9606.ENSP00000318066

UniGene: Hs.643497

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