在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ENHO Antibody, HRP conjugated

  • 中文名稱:
    ENHO兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA744265OB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ENHO Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Adropin antibody; C9orf165 antibody; Energy homeostasis associated protein antibody; Energy homeostasis-associated protein antibody; ENHO antibody; ENHO_HUMAN antibody; PRO830 antibody; UNQ470 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence from Human Adropin protein (37-54AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the regulation of glucose homeostasis and lipid metabolism.
  • 基因功能參考文獻:
    1. Serum adropin concentrations are decreased in Chinese T2DM patients, especially those overweight/obese. Adropin, associated with glucolipid homeostasis and insulin sensitivity, may implicate in the pathogenesis of T2DM. PMID: 29669965
    2. The highest adropin concentration was found in patients with P-Ch C (11.7+/-5.7 ng/ml) cirrhosis. PMID: 30260179
    3. Data suggest that serum and follicular fluid levels of adropin are down-regulated in women with PCOS (polycystic ovary syndrome) compared with control subjects; also, follicular fluid levels of adropin are lower than serum levels of adropin. PMID: 28937295
    4. significant association between maternal and umbilical adropin levels and the presence and severity of preeclampsia PMID: 28672759
    5. Adropin is coupled with biological clock activity. In mouse liver, ENHO expression has a diurnal rhythm that peaks at the end of maximal nutrient intake in the dark. The nuclear receptors ROR-alpha/gamma and Rev-erb may couple adropin synthesis with circadian rhythms in carbohydrate and lipid metabolism.In humans, associations between plasma adropin concentrations and LDL-C suggest a link with hepatic lipid metabolism. PMID: 29331507
    6. An increase in maternal serum adropin level was found in preeclampsia. PMID: 28501281
    7. Analysis of midluteal endometrial biopsies revealed an inverse correlation between endometrial EOGT and ENHO expression and body mass index. Obesity impairs the EOGT-adropin axis in decidual cells, which in turn points toward a mechanistic link between metabolic disorders and adverse pregnancy outcome. PMID: 29244071
    8. Serum adropin concentrations are negatively associated with renal function. PMID: 27546995
    9. High adropin expression is associated with polycystic ovary syndrome. PMID: 26969461
    10. There were no significant differences among the groups of systemic sclerosis (SSc) and controls in terms of ENHO gene expressions. There was no significant difference between the limited and diffuse cutaneous subtypes of SSc in terms of serum adropin level and ENHO gene expression. Moreover, serum adropin level and ENHO gene expression were not associated with the disease activity and severity indexes. PMID: 27079850
    11. Enho mutations plays a critical role in activating endothelial cells during neutrophil recruitment and neutrophil-endothelium cell interactions under IL-1 and TNF-alpha-induced vascular inflammation and increases susceptibility to MPOANCA associated lung injury. PMID: 27333037
    12. In HD patients, lower plasma adropin concentration is associated with dyslipidemia. Major homozygosity of RXRA seems to have an opposite effect on plasma adropin compared with that of ENHO rs2281997 PMID: 27449397
    13. Data suggest that serum adropin (ENHO) levels in normal, overweight, and obese adults negatively correlate with vascular stiffness (using common carotid artery) and adiposity (using abdominal visceral fat), and positively correlate with plasma nitric oxide levels (using nitrite/nitrate) and cardiorespiratory fitness; aerobic exercise training up-regulates serum adropin. PMID: 27897440
    14. The adropin levels of metabolic syndrome, obesity, and control groups also showed no difference PMID: 26226125
    15. Circulating adropin levels were determined lower in patients with endometrial cancer than in a control group. PMID: 26172926
    16. Lipids originating either from the diet or from endogenous production appear to positively affect plasma adropin concentrations in humans. PMID: 26435060
    17. Serum adropin levels were significantly lower in obese children; however, there was no correlation between serum adropin levels and blood pressure variables. PMID: 26030787
    18. Adropin as a novel energy factor likely has the ability to regulate blood pressure PMID: 25913544
    19. Serum adropin level was negatively correlated with carotid beta-stiffness and positively correlated with plasma NOx level and cardiorespiratory fitness PMID: 26371163
    20. Adropin levels are lower in patients with late saphenous vein graft occlusion and these reduced adropin levels, together with other factors, may lead to saphenous vein graft occlusion PMID: 25282140
    21. decreased serum adropin levels are associated with the presence of acute myocardial infarction in coronary artery disease patients PMID: 24731968
    22. Assessment of serum adropin concentrations may provide a reliable indicator of fatty liver disease in obese adolescents PMID: 24468600
    23. cord blood adropin levels were positively correlated with gestational age and placental weight but not with other fetal growth parameters. PMID: 24284417
    24. Plasma adropin levels were found to be a new marker for diagnosing endothelial dysfunction in type 2 diabetes mellitus. PMID: 24113736
    25. Release of adropin in the fed condition regulates fuel selection in skeletal muscle, promoting glucose oxidation over fat oxidation. The molecular mechanisms of adropin's effects involve acetylation (suggesting inhibition) of the transcriptional co-activator PGC1alpha, reducing PDK4 and CPT1B activity. Increased PGC1alpha acetylation by adropin may be mediated by inhibiting Sirtuin-1 (SIRT1), a PGC1alpha deacetylase. PMID: 24848071
    26. The mean maternal and cord serum adropin in a gestational diabetes mellitus group were significantly lower than those of control women (P=0.01 and P<0.001, respectively). PMID: 23314506
    27. Adropin is an independent risk factor for cardiac syndrome X (CSX). PMID: 23356444
    28. Although males exhibit higher adropin levels that are reduced by obesity, aging and markers of insulin resistance are associated with low plasma adropin irrespective of sex. PMID: 22872690
    29. Plasma adropin levels were examined in 45 men and 85 woman. Adropin levels are higher in men than woman. Obesity is associated with low adropin levels in men. Aging and metabolic risk factors are associated with low adropin levels, irrespective of sex. PMID: 22872690
    30. Plasma adropin levels are regulated dietary macronutrients increasing with dietary fat content. Fasting suppresses plasma adropin. Adropin's actions are required for preventing insulin resistance, dyslipidemia and impaired glucose tolerance. PMID: 22318315
    31. a potential endothelial protective role of adropin that is likely mediated via upregulation of endothelial NO synthase expression through the VEGFR2-phosphatidylinositol 3-kinase-Akt and VEGFR2-extracellular signal regulated kinase 1/2 pathways. PMID: 20837912
    32. Adropin has an endothelial protective function mediated via upregulation of eNOS expression through the VEGFR2-PI3K-Akt and VEGFR2-ERK1/2 pathways. Adropin therapy may thus be useful for limiting diseases characterized by endothelial dysfunction. PMID: 20837912
    33. Adropin is the name given to the secreted peptide encoded by the ORF in C9orf165. In mice, it is abundant in liver where it is regulated by dietary macronutrients. Adropin regulates expression of genes involved in lipogenesis and adipogenesis. PMID: 19041763

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 組織特異性:
    Expressed in liver and brain.
  • 數據庫鏈接:

    HGNC: 24838

    KEGG: hsa:375704

    STRING: 9606.ENSP00000382675

    UniGene: Hs.522085



主站蜘蛛池模板: 男人扒开女人双腿猛进免费视频| 天堂网www中文在线| 午夜美女裸体福利视频| 极品少妇被猛得白浆直喷白浆小说 | 人妻激情乱人伦| 国产精品久久久久久久久久直播| 欧美精品videosex性欧美| 狂野av人人澡人人添| 欧美成人精品 一区二区三区| 亚洲愉拍二区一区三区| 亚洲色婷婷一区二区三区| 内射人妻无套中出无码| 久久久久 亚洲 无码 av 专区| 中文在线天堂а√在线| 熟女内射v888av| 亚洲精品无码av专区最新| 国产激情综合在线看| 熟妇高潮精品一区二区三区| 国产精品免费观看久久| 亚洲欧美日韩二三区在线| 国产乱子伦一区二区三区四区五区 | 尤物精品国产第一福利网站| 国产成人精品日本亚洲第一区| 中文字幕av高清片| 热の综合热の国产热の潮在线| 国产精品毛多多水多| 国产精品视频免费播放| 国产99视频精品专区| 免费国产污网站在线观看| 丁香啪啪综合成人亚洲| 欧美乱码精品一区二区三区| 久久精品无码专区免费青青| 亚洲免费观看视频| 日韩综合无码一区二区| 国产在线视频天天综合网| 99精品丰满人妻无码a片| 中文字幕无码家庭乱欲| 亚洲人精品午夜射精日韩| 激情射精爆插热吻无码视频| 国产免费网站看v片在线无遮挡| 亚洲 另类 熟女 字幕|