在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EMX2 Antibody

  • 中文名稱:
    EMX2兔多克隆抗體
  • 貨號:
    CSB-PA007657LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: Rat brain tissue, Mouse brain tissue
      All lanes: EMX2 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 29, 19 kDa
      Observed band size: 29 kDa
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007657LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EMX2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EMX2
  • 別名:
    Empty spiracles homeobox 2 antibody; Empty spiracles homolog 2 (Drosophila) antibody; Empty spiracles homolog 2 antibody; Empty spiracles like protein 2 antibody; Empty spiracles-like protein 2 antibody; EMX 2 antibody; EMX2 antibody; EMX2_HUMAN antibody; Homeobox protein EMX 2 antibody; Homeobox protein EMX2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Rat, Mouse
  • 免疫原:
    Recombinant Human Homeobox protein EMX2 protein (75-141AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,EMX2 Antibody (CSB-PA007657LA01HU),的標記方式是Non-conjugated。對于EMX2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA007657LB01HU EMX2 Antibody, HRP conjugated ELISA
    FITC CSB-PA007657LC01HU EMX2 Antibody, FITC conjugated
    Biotin CSB-PA007657LD01HU EMX2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
  • 基因功能參考文獻:
    1. EMX2 is frequently down-regulated in human colorectal cancer, and down-regulation of EMX2 is a prognostic marker for disease-free and overall survival. PMID: 28830374
    2. Emx2 is a novel promising tool for therapy of glioblastoma and prevention of its recurrences. PMID: 27191499
    3. EMX2 inhibits proliferation and tumorigenesis through inactivation of the Wnt/beta-catenin pathway in CRC cells. PMID: 27712600
    4. EMX2 expression was down-regulated in lung SCC tissue compared to matched adjacent normal tissue. EMX2 expression was associated with improved overall survival. Knockdown promoted chemo-resistance and cell migration. PMID: 26132438
    5. Although it is uncommon (0.19%), EMX2 is the first gene identified that if perturbed may cause isolated incomplete mullerian fusion. PMID: 25577462
    6. Deletions of EMX2 have been associated with a wide range of DSD. PMID: 24975717
    7. EMX2 expression is downregulated in advanced cases of malignant pleural mesothelioma and may serve as an important prognostic and predictive molecular biomarker of progression-free survival. PMID: 25023662
    8. downregulation of empty spiracles homeobox 2 (EMX2) was associated with tumor progression and may be a critical factor in the carcinogenesis and progression of endometrial cancer PMID: 23370654
    9. EMX2 expression led to inhibition of cell proliferation and Wnt signaling pathway both in vitro and in a gastric cancer xenograft model in vivo. PMID: 23029345
    10. Study analyzed mutations of EMX2 gene in 45 prostate carcinomas, 51 non-small cell lung cancers, 43 gastric carcinomas, 44 colorectal carcinomas, and 43 breast carcinomas by polymerase chain reaction and single-strand conformation polymorphism assay. PMID: 21917011
    11. Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma. PMID: 21726823
    12. Data show that human teneurin-1 is directly regulated by EMX2 at a conserved promoter region upstream of the transcription start site, and identify and characterize the EMX2 dependent promoter element of human teneurin-1. PMID: 21651764
    13. promoter. Restoration of EMX2 expression in lung cancer cells lacking endogenous EMX2 expression suppressed cell proliferation and invasive phenotypes PMID: 20697358
    14. EMX2 gene has been reported in schezencephaly (cleft brain) including epilepsy in some patients. PMID: 12185771
    15. In these studies we identify and characterize the regulation of EMX2 by HOXA10. PMID: 12482956
    16. Endometrial EMX2 expression is aberrant in women with endometriosis and is mediated by altered HOXA10 expression. PMID: 15126568
    17. EMX2 levels in cortical progenitors of EMX2 transgenic mice disproportionately specify sizes and positions of primary cortical areas. PMID: 15294144
    18. It is unlikely that the EMX2 or PTEN gene variants investigated contribute to risk for initiation and/or development of endometriosis. PMID: 17563403
    19. provide results of EMX2 sequencing in 39 new schizencephaly patients, detecting no pathogenic mutations PMID: 18409201
    20. These data support recent reports that EMX2 but not PAX6 is more directly involved in arealization, highlighting that analysis of human development allows better spatio-temporal resolution than studies in rodents. PMID: 18973570

    顯示更多

    收起更多

  • 相關疾病:
    Schizencephaly (SCHZC)
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    EMX homeobox family
  • 組織特異性:
    Cerebral cortex.
  • 數據庫鏈接:

    HGNC: 3341

    OMIM: 269160

    KEGG: hsa:2018

    STRING: 9606.ENSP00000358202

    UniGene: Hs.202095



主站蜘蛛池模板: 国产精品婷婷久久爽一下| 人妻系列无码专区无码中出| 亚洲一区二区三区乱码在线欧洲| 69sex久久精品国产麻豆| 少妇性俱乐部纵欲狂欢电影| 日本道精品一区二区三区| 久久这里只有是精品23| 国产精品成人一区二区三区| 久激情内射婷内射蜜桃| 性欧美性另类巨大| 超薄丝袜足j好爽在线观看| 日本丰满老妇bbw| 国产三级精品三级在线观看| 亚洲色偷偷色噜噜狠狠99网| 午夜时刻免费入口| 国产a精彩视频精品视频下载| 被窝的午夜无码福利专区| 国产精品免费久久久久电影| 免费裸体美女网站| 欧美性受xxxx黑人xyx性爽| 狠狠久久噜噜熟女| 国内精品久久久久久久影院| 亚洲国产综合在线区尤物| 精品国产一区二区三区久久| 天堂一区人妻无码| 成人电线在线播放无码| 亚洲伊人情人综合网站| 国产精品无码v在线观看| 色噜噜狠狠色综合成人网| 婷婷五月日韩av永久免费| 衣服被扒开强摸双乳18禁网站| 国产亚av手机在线观看| 久久久久久国产精品无码超碰| 日本国产网曝视频在线观看| 亚洲精品图片区小说区| 老熟女乱子伦| 又色又爽又黄的gif动态图| 久久婷婷狠狠综合激情| av无码精品一区二区三区四区| 色av综合av综合无码网站| 色噜噜亚洲男人的天堂|