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  4. EMB Antibody, FITC conjugated

EMB Antibody, FITC conjugated

  • 中文名稱：
    EMB兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA754239LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EMB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EMB
  • 別名：
    Emb antibody; EMB_HUMAN antibody; Embigin antibody; Embigin homolog (mouse) antibody; embigin homolog antibody; MGC71745 antibody; OTTHUMP00000161812 antibody; OTTHUMP00000221477 antibody; OTTHUMP00000221478 antibody; OTTHUMP00000221479 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Embigin protein (285-327AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.
  • 基因功能參考文獻：
    1. Study reports elevated expression of Embigin in pancreatic ductal adenocarcinoma and shows its novel functions in regulating cell proliferation, migration, and invasion. PMID: 25773908
    2. embigin is regulated by HOXC8 and its loss plays an important role in the progression of breast tumors PMID: 26090721
    3. Data show that Gp70 (embigin) was negative in all normal, adjacent non-neoplastic and PIN lesions and only a very small percentage of cases. PMID: 21787388
    4. Reports the original cloning of the mouse embigin gene, referred to as gp70, from embryonal carcinoma cells. PMID: 2963822
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.
  • 數據庫鏈接：

    HGNC: 30465

    OMIM: 615669

    KEGG: hsa:133418

    STRING: 9606.ENSP00000302289

    UniGene: Hs.561411



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