在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ELOVL1 Antibody

ELOVL1 Antibody

  • 中文名稱：
    ELOVL1兔多克隆抗體
  • 貨號：
    CSB-PA939360
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA939360(ELOVL1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, A375 cells, Primary antibody: CSB-PA939360(ELOVL1 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    ELOVL1
  • 別名：
    ELOVL1; SSC1; CGI-88; Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1; ELOVL FA elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human ELOVL1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
  • 基因功能參考文獻：
    1. ELOV1 promotes very long-chain fatty acid accumulation X-linked adrenoleukodystrophy and is inhibited by CoA esters of bezafibrate and gemfibrozil. PMID: 25499606
    2. Results suggest that inhibition of atty acid elongase 1 (ELOVL1) may be an underlying mechanism by which Lorenzo's oil exerts its action. PMID: 24489110
    3. down-regulation of ELOVL1 had a comprehensive effect on the synthesis of very long chain ceramides which possibly point to a requirement for ELOVL1 expression for full CerS2-activity. PMID: 23538298
    4. ELOVL1 activity is regulated with the ceramide synthase CERS2, an enzyme essential for C24 sphingolipid synthesis. PMID: 20937905
    5. The authors identify ELOVL1 (elongation of very-long-chain-fatty acids) as the single elongase catalysing the synthesis of both saturated VLCFA (C26:0) and mono-unsaturated VLCFA (C26:1). PMID: 20166112

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ELO family, ELOVL1 subfamily
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14418

    OMIM: 611813

    KEGG: hsa:64834

    STRING: 9606.ENSP00000361536

    UniGene: Hs.25597



主站蜘蛛池模板： 亚洲精品无码久久久久久| 人妻丰满熟av无码区hd| 美丽的熟妇中文字幕| 欧美人与动牲交xxxxbbbb| 国内揄拍国内精品对白| 大胸美女污污污www网站| 天堂中文在线www天堂在线| 午夜免费啪视频| 国产亚洲精品久久久美女18黄| 永久免费精品成人网站| 午夜福利啪啪片| 亚洲已满18点击进入在线看片| 四虎永久在线高清国产精品| 99精品国产高清一区二区麻豆| 久久久国产精品| 麻豆 美女 丝袜 人妻 中文| 老司机深夜18禁污污网站| 亚洲精品国男人在线视频| 亚洲国产av美女网站| 无码人妻aⅴ一区二区三区有奶水| 国产精品久久久久久无码五月 | 久久久久久国产精品美女| 国内少妇高潮嗷嗷叫在线播放| 欧美老妇与禽交| 免费人成年激情视频在线观看 | 亚洲欧美在线制服丝袜国产| 14萝自慰专用网站| 爱性久久久久久久久| 亚洲美女高清aⅴ视频免费| 亚洲人成未满十八禁网站 | 欧美乱码精品一区二区三区| 亚洲欧美日韩国产另类电影| 毛片无遮挡高清免费| 99久久婷婷国产综合精品电影| 日本熟妇乱人伦xxxx| 国产午夜福利在线观看视频_ | 亚洲精品一卡2卡三卡4卡| 亚洲成av人片不卡无码| 乱码午夜-极国产极内射| 午夜亚洲影院在线观看| 日韩精品一区二区三区视频|