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  4. ELMO3 Antibody, Biotin conjugated

ELMO3 Antibody, Biotin conjugated

  • 中文名稱：
    ELMO3兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA846590LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ELMO3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ELMO3
  • 別名：
    CED 12 antibody; Ced 12 homolog 3 antibody; CED12 antibody; ELMO 3 antibody; ELMO3 antibody; ELMO3_HUMAN antibody; Engulfment and cell motility 3 antibody; Engulfment and cell motility protein 3 antibody; FLJ13824 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Engulfment and cell motility protein 3 protein (464-596AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 基因功能參考文獻：
    1. the silencing of ELMO3 inhibited cell proliferation, invasion, metastasis, and F-actin polymerization, and induced Gap 1 (G1) phase cell cycle arrest, demonstrating that ELMO3 is involved in the processes of growth, invasion and metastasis of Colorectal Cancer PMID: 27999268
    2. The purpose of this study was to asses ELMO3 expression in postoperatively irradiated head and neck squamous cell carcinoma patients. PMID: 28039609
    3. The over-expression of ELMO3 was a potential diagnostic and prognostic marker for non-small cell lung cancer. PMID: 26191257
    4. The present study reports the first characterization of the ELMO3 promoter and suggests a significant role of CDX2 in the basal transcriptional regulation of the intestine-specific expression of ELMO3, possibly through interaction with SP1. PMID: 20127720
  • 亞細胞定位：
    Cytoplasm.
  • 數據庫鏈接：

    HGNC: 17289

    OMIM: 606422

    KEGG: hsa:79767

    STRING: 9606.ENSP00000377566

    UniGene: Hs.377416



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