在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ELMO2 Antibody

  • 中文名稱:
    ELMO2兔多克隆抗體
  • 貨號:
    CSB-PA007612GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ELMO2
  • 別名:
    CED 12 antibody; Ced 12 homolog 2 antibody; CED 12 homolog A antibody; CED 12A antibody; CED-12 antibody; ced-12 homolog 2 antibody; CED12 antibody; CED12 homolog A antibody; CED12; C. elegans; homolog of; 2 antibody; CED12A antibody; ELMO 2 antibody; ELMO-2 antibody; ELMO2 antibody; ELMO2_HUMAN antibody; Engulfment and cell motility 2 (ced 12 homolog; C. elegans) antibody; Engulfment and cell motility 2 antibody; Engulfment and cell motility gene 2 antibody; Engulfment and cell motility protein 2 antibody; FLJ11656 antibody; hCED 12A antibody; hCED-12A antibody; hCED12A antibody; KIAA1834 antibody; OTTHUMP00000031762 antibody; PH domain protein CED12A antibody; Protein ced 12 homolog A antibody; Protein ced-12 homolog A antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ELMO2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 基因功能參考文獻:
    1. These data suggest a novel link between Tiam1 and RhoG/ILK /ELMO2 pathway as upstream effectors of the Rac1-mediated phagocytic process in trabecular meshwork cells. PMID: 27539661
    2. studies demonstrate that Elmo2 is a new regulator of insulin-dependent Glut4 membrane translocation through modulating Rac1 activity and Akt membrane compartmentalization. PMID: 27226625
    3. findings highlight the necessity of ELMO2 for maintaining vascular integrity, specifically in intramembranous bones; loss-of-function mutations in ELMO2 cause intraosseous vascular malformation by impeding RAC1 signaling PMID: 27476657
    4. Axl has a role in phosphorylating the Elmo scaffold proteins to promote Rac activation and cell invasion PMID: 25332238
    5. uncovered a role for ELMO in the recruitment of ACF7 to the membrane to promote microtubule capture and stability PMID: 23184944
    6. Through its association with ELMO2, ILK plays key roles in the regulation of Rho GTPases and cross-talk pathways between adhesion and growth factor receptors. PMID: 22568984

    顯示更多

    收起更多

  • 相關疾病:
    Vascular malformation, primary intraosseous (VMOS)
  • 亞細胞定位:
    Cytoplasm. Cytoplasm, cytosol. Membrane.
  • 組織特異性:
    Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
  • 數據庫鏈接:

    HGNC: 17233

    OMIM: 606421

    KEGG: hsa:63916

    STRING: 9606.ENSP00000290246

    UniGene: Hs.210469



主站蜘蛛池模板: 水蜜桃色314在线观看| 麻豆成人久久精品综合网址| 少妇无码av无码专区| 一本大道久久久久精品嫩草| 无码精品日韩中文字幕| 国内午夜国产精品小视频| 无码人妻斩一区二区三区| 无人区一码卡二卡三乱码| 北条麻妃在线一区二区| 精品 日韩 国产 欧美 视频| 国产精品99久久精品| 精品日产一卡二卡| 亚洲另类激情专区小说| 久久99精品久久久大学生| 老妇高潮潮喷到猛进猛出| 国内永久福利在线视频图片| 亚洲国产精品ⅴa在线播放| 久久av无码αv高潮αv喷吹| 少妇性俱乐部纵欲狂欢电影| 成年免费视频播放网站推荐| 精品国产一区二区av麻豆 | 麻豆国产精品va在线观看| 蜜桃日本免费观看mv| 亚洲色中文字幕无码av| 亚洲色婷婷久久精品av蜜桃久久 | 欧美日韩一区二区三区自拍| 国产激情综合在线看| 狠狠躁天天躁中文字幕无码| 国产精品99精品无码视亚| 在线 无码 中文字幕 强 乱| 日韩人妻不卡一区二区三区| 久久午夜神器| 毛色毛片免费观看| 久久精品成人免费观看| 成人毛片100免费观看| 亚洲色婷婷久久精品av蜜桃| 无码一区二区三区老色鬼| 无码专区—va亚洲v专区| 久久亚洲精品11p| 国产精品亚洲w码日韩中文| 成在线人免费视频播放|