在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ELL Antibody

ELL Antibody

  • 中文名稱：
    ELL兔多克隆抗體
  • 貨號(hào)：
    CSB-PA795035
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from Jurkat cells and HeLa cells, using ELL antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ELL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ELL
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human ELL.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.
  • 基因功能參考文獻(xiàn)：
    1. The results indicate that p53 interferes with the interaction between ELL/EAF and ICE1 and represses transcription of small nuclear RNA genes by Pol II. PMID: 27268141
    2. This work reveals a previously unrecognized function for ELL as an E3 ubiquitin ligase for c-Myc and a potential tumour suppressor. PMID: 27009366
    3. The Tax oncogene enhances ELL incorporation into p300 and P-TEFb containing protein complexes to activate transcription. PMID: 26188510
    4. eleven-nineteen lysine-rich leukemia protein enhanced E2F1 deacetylation via recruitment of histone deacetylase 1 PMID: 24344198
    5. ELL is an essential player for RNA Pol II restart during cellular DNA damage response. PMID: 24127601
    6. Studies indicate that the super elongation complex (SEC) consisting of ELL, P-TEFb (CDK9) and MLL required for rapid transcriptional induction in the presence or absence of paused RNA polymerase II (Pol II). PMID: 22895430
    7. ELL has an early and essential role during rapid high-amplitude gene expression that is required for both Pol II pause site entry and release PMID: 22252557
    8. Our findings suggest that ELL and HIF-1alpha are binding partners and can modulate the functions of each other in hypoxia. PMID: 20166137
    9. In the Acute Myeloid Leukemia patients, detected MLL rearrangements consisting of MLL/AF6, MLL/AF9, MLL/AF17 , MLL/ELL and MLL partial tandem duplication. MLL rearrangement include chromosome translocation and partial tandem duplication. PMID: 16086288
    10. ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation PMID: 19447890

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    A chromosomal aberration involving ELL is found in acute leukemias. Translocation t(11;19)(q23;p13.1) with KMT2A/MLL1. The result is a rogue activator protein.
  • 亞細(xì)胞定位：
    Nucleus. Nucleus speckle. Nucleus, Cajal body.
  • 蛋白家族：
    ELL/occludin family
  • 組織特異性：
    Expressed in all tissues tested. Highest levels found in placenta, skeletal muscle, testis and peripheral blood leukocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 23114

    OMIM: 600284

    KEGG: hsa:8178

    STRING: 9606.ENSP00000262809

    UniGene: Hs.515260



主站蜘蛛池模板： 手机福利视频| 国产真实露脸乱子伦| av国産精品毛片一区二区视频| 男女啪啪高清无遮挡免费| 免费无码一区二区三区a片百度| 高潮毛片又色又爽免费| 亚洲色无码专区在线观看精品| 亚洲mv国产mv在线mv综合试看 | 精品视频一区二区三区在线观看| 大香线蕉伊人精品超碰| 国产成人亚洲精品无码车a| 丝袜足控一区二区三区| 亚洲丁香五月天缴情综合| 女人18毛片水真多| 亚洲欧洲日产国码韩国| 久青青在线观看视频国产 | 92午夜福利少妇系列| 一区二区国产高清视频在线 | 天天澡天天揉揉av在线| a毛片免费全部播放自慰| 大尺度无遮挡激烈床震网站| 中文字幕亚洲欧美日韩在线不卡| 精品国产黑色丝袜高跟鞋| 狼人亚洲国内精品自在线| 日本国产一区二区三区在线观看| 欧美精品色婷婷五月综合| 亚洲欧美日韩在线不卡| 男女裸体下面进入的免费视频| 人妻影音先锋啪啪av资源| 国产精品久久自在自线不| 无码人妻精一区二区三区| 伊人情人色综合网站| 亚洲中文字幕在线精品2021| 99er热精品视频| 一边添奶一边添p好爽视频| 久久天天躁夜夜躁狠狠i女人| 狠狠色狠狠色狠狠五月| 天天av天天翘天天综合网色鬼| 亚洲精品久久久www| 久热这里只有精品99在线观看| 欧美群妇大交群|