在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EIF3M Antibody

  • 中文名稱:
    EIF3M兔多克隆抗體
  • 貨號:
    CSB-PA745333DSR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: EIF3M antibody at 2.02µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: A549 whole cell lysate
      Lane 3: Mouse gonadal tissue
      Lane 4: Human placenta tissue
      Lane 5: Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 43, 28 kDa
      Observed band size: 43 kDa
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA745333DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA745333DSR1HU at dilution of 1:100
    • Immunoprecipitating EIF3M in Hela whole cell lysate
      Lane 1: Rabbit control IgG instead of (1µg) instead of CSB-PA745333DSR1HU in Hela whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
      Lane 2: CSB-PA745333DSR1HU (4µg) + Hela whole cell lysate (500µg)
      Lane 3: Hela whole cell lysate (20µg)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EIF3M Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EIF3M
  • 別名:
    B5 antibody; B5 receptor antibody; Dendritic cell protein antibody; eIF3m antibody; EIF3M_HUMAN antibody; Eukaryotic translation initiation factor 3 subunit M antibody; Fetal lung protein B5 antibody; FLJ29030 antibody; GA17 antibody; hfl B5 antibody; hFL-B5 antibody; PCI domain containing 1 (herpesvirus entry mediator) antibody; PCI domain-containing protein 1 antibody; PCID1 antibody; TANGO7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Eukaryotic translation initiation factor 3 subunit M protein (1-374AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IP
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.; (Microbial infection) May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
  • 基因功能參考文獻:
    1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
    2. eIF3m mediates regulation of tumorigenesis-related genes in human colon cancer PMID: 20838379
    3. Results demonstrate that B5 plays a major role in the initiation of HSV protein translation and could provide a novel target for strategies to prevent primary and recurrent herpetic disease. PMID: 20676407
    4. Cloned a previously uncharacterized human gene, designated hfl-B5, and showed that it encodes a type II cell surface membrane protein that can serve as a receptor for entry of HSV. PMID: 15919898
    5. Concluded that the C terminus of B5 contains a functional region that is important for the B5 receptor to mediate events in HSV entry. PMID: 15919899
    6. the human Tango7 counterpart, PCID1 (also known as EIF3M), impinged on caspase 9, revealing a new regulatory axis affecting the apoptosome PMID: 19483676

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    EIF-3 subunit M family
  • 組織特異性:
    Broadly expressed.
  • 數據庫鏈接:

    HGNC: 24460

    OMIM: 609641

    KEGG: hsa:10480

    STRING: 9606.ENSP00000436049

    UniGene: Hs.502244



主站蜘蛛池模板: 性强烈的欧美三级视频| 乱中年女人伦| 久久亚洲精品中文字幕| 欧美成妇人吹潮在线播放| 亚洲中字幕日产av片在线| 久久午夜伦鲁片免费无码| 我和亲妺妺乱的性视频| 国产精品人妻久久毛片| 亚洲精品久久国产精品| 国产98色在线 | 日韩| 亚洲第一se情网站| 午夜婷婷精品午夜无码a片影院| 日本亚州视频在线八a| 超碰免费公开| 50岁退休熟女露脸高潮| 亚洲国产精品嫩草影院永久| 成人三级视频在线观看一区二区| 性开放的女人aaa片| 日本人妻伦在线中文字幕| 日本黄漫动漫在线观看视频| 亚洲综合伊人久久大杳蕉| 人妻少妇精品视频一区二区三区| 国产精品成人亚洲777| 亚洲精品综合欧美一区二区| 青青草大香焦在线综合视频| 久久99精品国产99久久6尤物| 欧美性生交活xxxxxdddd| 粗大的内捧猛烈进出视频| 久久99精品久久久久婷婷| 色v99在线影院| 久久99精品国产免费观观| 乱人伦人妻中文字幕无码| 一区二区三区波多野结衣在线观看| 少妇爽到呻吟的视频| 国产成人精品电影在线观看| 亚洲爆乳无码一区二区三区| 亚洲欧洲成人a∨在线观看| 香蕉视频在线精品视频| 无码人妻精品一区二区蜜桃百度 | 熟女人妻av完整一区二区三区 | 在线精品自偷自拍无码|