在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EIF3M Antibody

  • 中文名稱:
    EIF3M兔多克隆抗體
  • 貨號:
    CSB-PA745333DSR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: EIF3M antibody at 2.02µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: A549 whole cell lysate
      Lane 3: Mouse gonadal tissue
      Lane 4: Human placenta tissue
      Lane 5: Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 43, 28 kDa
      Observed band size: 43 kDa
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA745333DSR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA745333DSR1HU at dilution of 1:100
    • Immunoprecipitating EIF3M in Hela whole cell lysate
      Lane 1: Rabbit control IgG instead of (1µg) instead of CSB-PA745333DSR1HU in Hela whole cell lysate. For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
      Lane 2: CSB-PA745333DSR1HU (4µg) + Hela whole cell lysate (500µg)
      Lane 3: Hela whole cell lysate (20µg)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EIF3M Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EIF3M
  • 別名:
    B5 antibody; B5 receptor antibody; Dendritic cell protein antibody; eIF3m antibody; EIF3M_HUMAN antibody; Eukaryotic translation initiation factor 3 subunit M antibody; Fetal lung protein B5 antibody; FLJ29030 antibody; GA17 antibody; hfl B5 antibody; hFL-B5 antibody; PCI domain containing 1 (herpesvirus entry mediator) antibody; PCI domain-containing protein 1 antibody; PCID1 antibody; TANGO7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Eukaryotic translation initiation factor 3 subunit M protein (1-374AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC, IP
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.; (Microbial infection) May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
  • 基因功能參考文獻:
    1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
    2. eIF3m mediates regulation of tumorigenesis-related genes in human colon cancer PMID: 20838379
    3. Results demonstrate that B5 plays a major role in the initiation of HSV protein translation and could provide a novel target for strategies to prevent primary and recurrent herpetic disease. PMID: 20676407
    4. Cloned a previously uncharacterized human gene, designated hfl-B5, and showed that it encodes a type II cell surface membrane protein that can serve as a receptor for entry of HSV. PMID: 15919898
    5. Concluded that the C terminus of B5 contains a functional region that is important for the B5 receptor to mediate events in HSV entry. PMID: 15919899
    6. the human Tango7 counterpart, PCID1 (also known as EIF3M), impinged on caspase 9, revealing a new regulatory axis affecting the apoptosome PMID: 19483676

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    EIF-3 subunit M family
  • 組織特異性:
    Broadly expressed.
  • 數據庫鏈接:

    HGNC: 24460

    OMIM: 609641

    KEGG: hsa:10480

    STRING: 9606.ENSP00000436049

    UniGene: Hs.502244



主站蜘蛛池模板: 久久久国产打桩机| 色婷婷五月综合色啪网| 日日鲁鲁鲁夜夜爽爽狠狠视频97 | 伊人色合天天久久综合网| 天天做天天摸天天爽天天爱| 国产嫖妓风韵犹存对白| 成年免费视频播放网站推荐| 在线天堂资源www| 亚洲欧美日韩精品久久| 精品三级av无码一区| 啪啪后入内射日韩| 久久不见久久见www电影免费| 亚洲色欧美色2019在线| 刺激性视频黄页| 女狠狠噜天天噜日日噜| 国产av天堂亚洲国产av天堂| 波多野结av衣东京热无码专区| 久久久中文字幕日本无吗 | 亚洲中字慕日产2020| 国产成人精品无码播放| 美女裸体十八禁免费网站| 国产精品女同一区二区在线| 噜噜高清欧美内射短视频| 国产亚洲精品久久久久久牛牛| 亚洲一区激情校园小说| 人人澡人人妻人人爽人人蜜桃麻豆| 亚洲日本成本人观看| 色欲人妻aaaaaaa无码| 国产人无码a在线西瓜影音| 伊人av超碰伊人久久久| 国产精品久久午夜夜伦鲁鲁| 无码av最新无码av专区| 99精品国产福利一区二区| 中文字幕一精品亚洲无线一区 | 婷婷成人丁香五月综合激情| 国产精品久免费的黄牛仔短裤| 亚洲精品国产一区黑色丝袜| 成人做爰www网站视频| 窝窝午夜看片成人精品| 亚欧av无码乱码在线观看性色| 一本一道波多野结衣av一区|