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EIF3L Antibody

  • 中文名稱:
    EIF3L兔多克隆抗體
  • 貨號:
    CSB-PA002298
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HuvEc cells using eIF3L Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    EIF3L
  • 別名:
    eIEF associated protein HSPC021 antibody; EIF3EIP antibody; eif3l antibody; EIF3L_HUMAN antibody; EIF3S11 antibody; EIF3S6IP antibody; Eukaryotic translation initiation factor 3 subunit 6 interacting antibody; Eukaryotic translation initiation factor 3 subunit 6-interacting protein antibody; Eukaryotic translation initiation factor 3 subunit E-interacting protein antibody; Eukaryotic translation initiation factor 3 subunit L antibody; eukaryotic translation initiation factor 3; subunit E interacting antibody; HSPC021 antibody; HSPC025 antibody; MSTP005 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human eIF3L.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.; (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2.
  • 基因功能參考文獻:
    1. These results indicate an interaction of human eIF3L with yellow fever virus NS5 and that eIF3L overexpression facilitates translation, which has potential implications for virus replication. PMID: 23800076
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    EIF-3 subunit L family
  • 數據庫鏈接:

    HGNC: 18138

    KEGG: hsa:51386

    STRING: 9606.ENSP00000416892

    UniGene: Hs.446852



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