EIF3L Antibody
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中文名稱:EIF3L兔多克隆抗體
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貨號:CSB-PA002298
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規格:¥1090
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圖片:
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其他:
產品詳情
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Uniprot No.:
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基因名:EIF3L
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別名:eIEF associated protein HSPC021 antibody; EIF3EIP antibody; eif3l antibody; EIF3L_HUMAN antibody; EIF3S11 antibody; EIF3S6IP antibody; Eukaryotic translation initiation factor 3 subunit 6 interacting antibody; Eukaryotic translation initiation factor 3 subunit 6-interacting protein antibody; Eukaryotic translation initiation factor 3 subunit E-interacting protein antibody; Eukaryotic translation initiation factor 3 subunit L antibody; eukaryotic translation initiation factor 3; subunit E interacting antibody; HSPC021 antibody; HSPC025 antibody; MSTP005 antibody
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宿主:Rabbit
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反應種屬:Human,Mouse
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免疫原:Synthesized peptide derived from the N-terminal region of Human eIF3L.
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式:Liquid
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應用范圍:WB, IF, ELISA
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推薦稀釋比:
Application Recommended Dilution WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:20000 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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功能:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.; (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2.
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基因功能參考文獻:
- These results indicate an interaction of human eIF3L with yellow fever virus NS5 and that eIF3L overexpression facilitates translation, which has potential implications for virus replication. PMID: 23800076
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亞細胞定位:Cytoplasm.
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蛋白家族:EIF-3 subunit L family
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數據庫鏈接:
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