在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EIF3I Antibody

EIF3I Antibody

  • 中文名稱：
    EIF3I兔多克隆抗體
  • 貨號：
    CSB-PA007538GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    EIF3I
  • 別名：
    eIF-3-beta antibody; eIF3 beta antibody; eIF3 p36 antibody; eIF3-beta antibody; eIF3-p36 antibody; eIF3i antibody; EIF3I_HUMAN antibody; EIF3S2 antibody; EIF3S2; formerly antibody; Eukaryotic translation initiation factor 3 subunit 2 antibody; Eukaryotic translation initiation factor 3 subunit 2 beta antibody; Eukaryotic translation initiation factor 3 subunit I antibody; eukaryotic translation initiation factor 3; subunit 2 (beta; 36kD antibody; eukaryotic translation initiation factor 3; subunit 2 beta; 36kDa antibody; eukaryotic translation initiation factor 3; subunit 2; formerly antibody; eukaryotic translation initiation factor 3; subunit I antibody; Predicted protein of HQ2242 antibody; PRO2242 antibody; TGF beta receptor interacting protein 1 antibody; TGF-beta receptor-interacting protein 1 antibody; TGFbeta receptor interacting protein 1 antibody; TGFbeta receptor-interacting protein 1 antibody; TRIP 1 antibody; TRIP-1 antibody; TRIP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human EIF3I
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
  • 基因功能參考文獻：
    1. EIF3i may affect vesicular stomatitis virus (VSV) growth by regulating the host antiviral response in HeLa cells. PMID: 29173589
    2. High eIF3i expression is associated with melanoma. PMID: 28193911
    3. Clusterin is an independent predictive factor for prognosis of hepatocellular carcinoma and it facilitates metastasis through EIF3I/Akt/MMP13 signaling. PMID: 25609201
    4. eIF3i is a proto-oncogene that drives colon oncogenesis by translationally upregulating COX-2 and activating the beta-catenin signaling pathway PMID: 24056964
    5. findings report that short hairpin RNA mediated depletion of TRIP-1 gene transcripts in A549 cells promotes epithelial-mesenchymal transition (EMT); knockdown of TRIP-1 dramatically increased A549 responsiveness to TGF-beta1 induction of EMT PMID: 21378021
    6. eIF3i overexpression fosters the integration of growth signals by mTOR into the mRNA translation process, promoting protein synthesis and tumor growth. PMID: 16929481
    7. Subunit b of the eIF3 complex directly binds to HCV IRES domain III via its N-terminal-RRM. PMID: 19059401
    8. TGF-beta receptor interacting protein 1 (TRIP-1), which we show inhibits fibroblast collagen contraction, is higher in fetal than adult fibroblasts PMID: 19329541

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    EIF-3 subunit I family
  • 數據庫鏈接：

    HGNC: 3272

    OMIM: 603911

    KEGG: hsa:8668

    STRING: 9606.ENSP00000362688

    UniGene: Hs.530096



主站蜘蛛池模板： 日韩日韩日韩日韩日韩| 日韩人妻中文无码一区二区三区| 搡老女人老妇女老熟妇| 久久人人爽人人爽人人片ⅴ| 国产精品性夜天天拍拍2021| 天天躁日日躁aaaxxⅹ| 萝卜视频高清免费视频日本| 妺妺窝人体色www婷婷| 久久96国产精品久久久| 97人妻免费碰视频碰免| 亚洲中文字幕aⅴ天堂| 国产成人精品123区免费视频| 国产真实露脸乱子伦原著| 国产成人精品无码一区二区三区| av片在线观看永久免费| 成 人免费va视频| 真实国产乱子伦对白视频不卡| a v 在线视频 亚洲免费| 国产成人一区二区不卡免费视频| 国内精品伊人久久久久影院麻豆| 青青青国产免a在线观看| 欧美老肥熟妇多毛xxxxx| 精品卡一卡二卡3卡高清乱码| 国产情侣真实露脸在线| 亚洲综合最新无码专区| 在线播放偷拍一区精品| 无码人妻aⅴ一区二区三区| 欧美三级欧美成人高清| 一区二区狠狠色丁香久久婷婷| 无码精品黑人一区二区三区| 亚洲欧美国产精品久久久久久久 | 乱子伦视频在线看| 国产精品香港三级国产av| 国产人妻久久精品二区三区| 欧美日韩精品suv| 日韩不卡1卡2卡三卡2021精品推荐| 2021国产精品自在自线| 国产成人免费97在线| 亚洲精品国产成人精品软件| 成人午夜精品无码区久久| 国产第一页屁屁影院|