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  4. EIF1 Antibody

EIF1 Antibody

  • 中文名稱：
    EIF1兔多克隆抗體
  • 貨號：
    CSB-PA007503LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of A549 cells with CSB-PA007503LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EIF1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EIF1 antibody; SUI1Eukaryotic translation initiation factor 1 antibody; eIF1 antibody; A121 antibody; Protein translation factor SUI1 homolog antibody; Sui1iso1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Eukaryotic translation initiation factor 1 protein (2-113AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，EIF1 Antibody (CSB-PA007503LA01HU)，的標記方式是Non-conjugated。對于EIF1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA007503LB01HU EIF1 Antibody, HRP conjugated ELISA
    FITC CSB-PA007503LC01HU EIF1 Antibody, FITC conjugated
    Biotin CSB-PA007503LD01HU EIF1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA.
  • 基因功能參考文獻：
    1. Anti-Sui1 could be utilized as a supplementary serological marker. PMID: 26386724
    2. eIF1A is a novel component of the Ago2-centred RNA-induced silencing complexes (RISCs) and augments Ago2-dependent RNAi and miRNA biogenesis. PMID: 26018492
    3. eEF4GI shares this activity and also interacts with eIF1. PMID: 25738462
    4. eIF1, eIF1A, eIF3j, and the eIF2-GTP-Met-tRNAi ternary complex stably bind to the 43 S preinitiation complex PMID: 25246524
    5. Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complex PMID: 23293029
    6. This study provides mechanistic insight into the role of eIF5-carboxyl terminal domain's dynamic interplay with eIF1 and eIF2beta. PMID: 22813744
    7. show that the stringency of start codon selection (preferential utilization of optimal start sites) is increased to a surprising degree by overexpressing eIF1 PMID: 20921384

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  • 蛋白家族：
    SUI1 family
  • 數據庫鏈接：

    HGNC: 3249

    KEGG: hsa:10209

    STRING: 9606.ENSP00000419449

    UniGene: Hs.150580



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