在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EI24 Antibody

EI24 Antibody

  • 中文名稱：
    EI24兔多克隆抗體
  • 貨號：
    CSB-PA099944
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA099944(EI24 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    EI24; PIG8; Etoposide-induced protein 2.4 homolog; p53-induced gene 8 protein
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human EI24
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:10-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy.
  • 基因功能參考文獻：
    1. EI24 is an essential player in ubiquitin-proteasome system-autophagy crosstalk via degradation of RING E3 ligases. PMID: 27541728
    2. Low EI24 expression is associated with triple negative breast cancer. PMID: 28038450
    3. Low EI24 and high IGF-1R expressions in lung cancer patients. PMID: 26342551
    4. Findings establish EI24 as a critical suppressor of tumor progression. PMID: 24280371
    5. Ei24 can bind specifically to IMPbeta1 and IMPalpha2 to impede their normal role in nuclear import. PMID: 24821838
    6. Ei24 is a novel E2F1 target gene contributing to the survival of p53-deficient cells upon UVC irradiation and thus may have a potential significance as a therapeutic target of certain chemotherapy for treating p53-deficient tumors. PMID: 24014029
    7. our data suggest that inactivation of EI24 and CHEK1 through two independent mechanisms contributes to the development of CACX. PMID: 21154811
    8. LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance. PMID: 21803008
    9. identify the EI24/PIG8 status as a potentially new prognostic marker of chemotherapy responsiveness PMID: 17981155

    顯示更多

    收起更多

  • 相關疾病：
    EI24 is on a chromosomal region frequently deleted in solid tumors, and it is thought to play a role in breast and cervical cancer. Particularly, expression analysis of EI24 in cancerous tissues shows that EI24 loss is associated with tumor invasiveness.
  • 亞細胞定位：
    Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    EI24 family
  • 數據庫鏈接：

    HGNC: 13276

    OMIM: 605170

    KEGG: hsa:9538

    STRING: 9606.ENSP00000278903

    UniGene: Hs.643514



主站蜘蛛池模板： 国产精品sp调教打屁股| 久久香蕉国产线看观看怡红院妓院| 色偷偷av男人的天堂| 亚洲成色在线综合网站| 曰本极品少妇videossexhd| 永久免费毛片在线播放| 女人爽到高潮视频免费直播 | 国内精品久久久久影院亚瑟| 亚洲欧美色中文字幕在线| 极品尤物一区二区三区| 极品尤物被啪到呻吟喷水 | 西西人体大胆无码视频| 一区二区三区无码按摩精油| 特级毛片a片久久久久久| 亚洲精品无码不卡在线播he| 无码国产精品一区二区免费虚拟vr| 黑人上司粗大拔不出来电影| 国产精品乱子伦xxxx| 最新在线精品国自产拍福利| 国产精品久久久久久超碰| 免费超爽大片黄| 亚洲伊人丝袜精品久久| 日本强伦姧人妻久久影片| 蜜桃mv在线播放免费观看视频 | a 'v片欧美日韩在线| 免费视频好湿好紧好大好爽| 国产欧美一区二区三区免费视频| 西西人体www大胆高清| 中文字幕人妻少妇引诱隔壁| 亚洲a综合一区二区三区| 国产乱码二卡3卡四卡| 99久久免费精品高清特色大片| 人妻无码中文字幕免费视频蜜桃 | 少妇精品偷拍高潮少妇小说| 亚洲一区二区三区国产精品无码| 国产精品一久久香蕉国产线看观看| 久久久久国色av免费看| 久久久久欧美精品| 8ⅹ8x擦拨擦拨成人免费视频| 欧美另类 自拍 亚洲 图区| 国内大量偷窥精品视频|