在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EHD1 Antibody

  • 中文名稱:
    EHD1兔多克隆抗體
  • 貨號:
    CSB-PA884470LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: EHD1 antibody at 12µg/ml + MDA-MB-231 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 61 kDa
      Observed band size: 61 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA884470LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EHD1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CDABP0131 antibody; EH domain containing 1 antibody; EH domain-containing protein 1 antibody; EHD1 antibody; EHD1_HUMAN antibody; FLJ42622 antibody; FLJ44618 antibody; H PAST antibody; hPAST1 antibody; PAST antibody; PAST homolog 1 antibody; PAST1 antibody; Testilin antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human EH domain-containing protein 1 protein (401-498AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,EHD1 Antibody (CSB-PA884470LA01HU),的標記方式是Non-conjugated。對于EHD1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA884470LB01HU EHD1 Antibody, HRP conjugated ELISA
    FITC CSB-PA884470LC01HU EHD1 Antibody, FITC conjugated
    Biotin CSB-PA884470LD01HU EHD1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis.
  • 基因功能參考文獻:
    1. Results suggest that EHD1 is a cisplatin (CDDP)-resistant gene that suppresses DNA adduct-induced apoptosis by modulating intracellular CDDP concentrations. PMID: 27411790
    2. this study shows that overexpression of EHD1 induced the epithelial-mesenchymal transition and increased the metastatic potential of lung cancer cells in vitro and in vivo PMID: 27531895
    3. RAB11FIP3 combines with Eps15 homology domain 1 to promote the endocytosis recycling of phosphorylation of epithelial growth factor receptor. PMID: 28215104
    4. van der Waals interactions should be the main consideration when we design peptide inhibitors of EHD1 EH domain with high affinities. PMID: 26465136
    5. Authors found that Eps15-homology domain 1 (EHD1), a protein that associates with the endocytic recycling compartment (ERC), colocalizes with active R-Ras in transiently expressed HeLa cells. PMID: 26378252
    6. that Molecule Interacting with CasL Like-1 and Eps15 Homology Domain protein 1 differentially influence microtubule dynamics during early and late mitosis PMID: 25287187
    7. Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. PMID: 25595798
    8. Data indicate that concordant transforming growth factor-beta1 (TGFbeta-1) positive and EH-domain containing 1 (EHD1) negative as a strong favorable prognosis factor in non-small cell lung cancer (NSCLC). PMID: 24946721
    9. MICAL-L1-mediated recruitment of EHD1 to Src-containing recycling endosomes is required for the release of Src from the perinuclear endocytic recycling compartment in response to growth factor stimulation. PMID: 24481818
    10. evidence that the functions of both EHD1 and EHD4 are primarily in TRE membrane vesiculation, whereas EHD3 is a membrane-tubulating protein. PMID: 24019528
    11. the lipid modifier cPLA2alpha and EHD1 are involved in the vesiculation of CD59-containing endosomes PMID: 22456504
    12. Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function PMID: 22284051
    13. EHD1 is involved in the control of CD59 transport from pre-sorting endosomes to the ERC in a PKC-dependent manner PMID: 20961375
    14. A new class of cardiac trafficking proteins(EHD1, EHD2, EHD3, EHD4) regulates cardiac membrane protein targeting. PMID: 20489164
    15. The results indicate that NPF is the preferred binding motif for the EHD1 EH-domain, but both the DPF and GPF motifs are capable of binding with lower affinity. PMID: 19798736
    16. These data implicate MICAL-L1 as an unusual type of Rab effector that regulates endocytic recycling by recruiting and linking EHD1 and Rab8a on membrane tubules. PMID: 19864458
    17. A tubular EHD1-containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane PMID: 12032069
    18. EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1. PMID: 12121420
    19. a novel interacting partner for EHD1, rabenosyn-5, was revealed. PMID: 15020713
    20. ATP binding is required for oligomerization of mRme-1/EHD1, which in turn is required for its association with endosomes PMID: 15710626
    21. Data support a role for EHD1 in beta1 integrin recycling, and demonstrate a requirement for EHD1 in integrin-mediated downstream functions. PMID: 17284518
    22. Rab8a and Myosin Vb colocalize to a tubular network containing EHD1 and EHD3, which does not contain Rab11a. PMID: 17507647
    23. Solution structure of the 133 C-terminal residues of EHD1, which includes the EH domain, was solved. PMID: 17899392
    24. Results show that EHD1 undergoes serine-phosphorylation, and suggest that EHD1 phosphorylation occurs between early endosomes and the endocytic recycling compartment. PMID: 18661112
    25. Data show that EH domain mutant (K483E) that associates exclusively with punctate membranes displayed decreased binding to phosphatidylinositol-4-phosphate and other phosphoinositides. PMID: 19369419

    顯示更多

    收起更多

  • 亞細胞定位:
    Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
  • 組織特異性:
    Highly expressed in testis.
  • 數據庫鏈接:

    HGNC: 3242

    OMIM: 605888

    KEGG: hsa:10938

    STRING: 9606.ENSP00000320516

    UniGene: Hs.523774



主站蜘蛛池模板: 台湾无码av一区二区三区| 日本亲近相奷中文字幕| 国产真实野战在线视频| 久久婷婷五月综合中文字幕| 国产精品亚亚洲欧关中字幕 | 亚洲伊人色欲综合网无码中文| 国产精品视频一区二区三区不卡| 色综合久久中文综合网| 亚洲视频日本有码中文| 国产成人人综合亚洲欧美丁香花| 欧美日韩人妻精品一区二区在线| 午夜福利精品导航凹凸| 成人性生交大片免费看视频app| 日韩成人无码| 激情97综合亚洲色婷婷五 | 国产精品va在线观看老妇女| 国产三级精品三级在线观看| 久久精品国产99久久久古代| 四虎影视精品永久在线观看| 欧美成人午夜性视频| 国产一起色一起爱| 国产精品99久久久精品无码| 中文午夜乱理片无码| 亚洲精品无码久久久久av麻豆| 亚洲人成网线在线播放va蜜芽| 国产亚洲精品久久久久秋霞| 夜夜澡人摸人人添人人看 | 午夜精品久久久久久久喷水| 97久久精品无码一区二区| 日本天天日噜噜噜| 欧洲精品卡一卡二卡三| 欧美乱妇高清无乱码在线观看| 青青草国产精品日韩欧美| 国产精品无码久久综合网| 无码任你躁久久久久久| 内射干少妇亚洲69xxx| 强伦姧人妻免费无码电影| 国产乱码一区二区三区爽爽爽| 久久欧美一区二区三区性生奴| 亚洲aⅴ综合色区无码一区| 波多野无码黑人在线播放|