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  4. EFS Antibody

EFS Antibody

  • 中文名稱：
    EFS兔多克隆抗體
  • 貨號：
    CSB-PA007470GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    EFS
  • 別名：
    EFS antibody; CASS3Embryonal Fyn-associated substrate antibody; hEFS antibody; Cas scaffolding protein family member 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human EFS
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
  • 基因功能參考文獻：
    1. EFS and CASS4 protein function in the context of the larger CAS family group. [Review] PMID: 26119091
    2. we suggest that EFS should be considered as a novel tumor suppressor gene in prostate cancer. PMID: 25296736
    3. Analysis of 16 Uveal melanoma showed full methylation of the EFS CpG island in 8 (50%), no methylation in 5(31%)and partial methylation in 3 (19%)tumors. Kaplan-Meier analysis revealed higher risk of metastatic progression for tumors with EFS methylation. PMID: 21871071
  • 蛋白家族：
    CAS family
  • 組織特異性：
    The protein has been detected in lung and placenta.
  • 數據庫鏈接：

    HGNC: 16898

    OMIM: 609906

    KEGG: hsa:10278

    STRING: 9606.ENSP00000216733

    UniGene: Hs.24587



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