在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EFNB3 Antibody

EFNB3 Antibody

  • 中文名稱：
    EFNB3兔多克隆抗體
  • 貨號：
    CSB-PA007467ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA007467ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EFNB3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EFNB3
  • 別名：
    EFL 6 antibody; EFL6 antibody; EFNB 3 antibody; Efnb3 antibody; EFNB3_HUMAN antibody; EPH related receptor transmembrane ligand ELK L3 antibody; EPH related receptor transmembrane ligand ELKL3 antibody; EPH related receptor tyrosine kinase ligand 8 antibody; EPH-related receptor transmembrane ligand ELK-L3 antibody; EPH-related receptor tyrosine kinase ligand 8 antibody; Ephrin B3 antibody; Ephrin-B3 antibody; EphrinB3 antibody; EPLG 8 antibody; EPLG8 antibody; LERK 8 antibody; LERK-8 antibody; LERK8 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ephrin-B3 protein (28-226AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.; (Microbial infection) Acts as a receptor for nipah virus and hendra virus.
  • 基因功能參考文獻：
    1. The study provides evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrating that EFNB3 is a hypertension risk gene. PMID: 28272517
    2. Data suggest that molecules in the erythropoietin-producing hepatocellular receptor B family (EPHB) / ephrinB (EFNB) signalling pathways, specifically ephrin B3 and GRIP1, are involved blood pressure regulation. PMID: 27941904
    3. Data show that Ephrin B3 was concomitantly expressed with EphA2 and Ephrin A1 with higher Ephrin B3 levels found in non-squamous than in squamous tumors. PMID: 27533087
    4. Study found up-regulated expression of ephrinB3/EphB3 in intractable temporal lobe epilepsy patients and experimental temporal lobe epilepsy rats, which suggested that ephrinB3/EphB3 might be involved in the pathogenesis of temporal lobe epilepsy PMID: 26930615
    5. Findings suggest that EphrinB3 may be a relevant target for promoting remyelination in demyelinating disease PMID: 26687980
    6. Ephrin-B3 binds to B lymphocytes, most likely via a non-classical receptor, and induces migration of the memory B cell subpopulation. PMID: 21447033
    7. Phosphoproteomic profiling of nonsmall cell lung cancer cells reveals that ephrin B3 regulates pro-survival signaling through Akt1-mediated phosphorylation of the EphA2 receptor. PMID: 21413766
    8. evidence for an unknown ephrin-B3-binding cell-surface proteoglycan involved in cellular signalling PMID: 20925654
    9. EphrinB3 is a bona fide alternate receptor for NiV entry, and two residues in the G-H loop of the ephrin B-class ligands are critical determinants of NiV receptor activity. PMID: 16477309
    10. Immunohistochemistry shows robust staining for phosphorylated ephrin-B and ephrin-B3 in invading glioblastoma cells. PMID: 16951161
    11. Transgenic EphB1 and ephrin-B3 cooperatively regulate the proliferation and migration of neural progenitors in the hippocampus PMID: 18057206
    12. report the crystal structures of the NiV-G both in its receptor-unbound state and in complex with ephrin-B3, providing, to our knowledge, the first view of a paramyxovirus attachment complex in which a cellular protein is used as the virus receptor PMID: 18632560

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Ephrin family
  • 組織特異性：
    Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.
  • 數據庫鏈接：

    HGNC: 3228

    OMIM: 602297

    KEGG: hsa:1949

    STRING: 9606.ENSP00000226091

    UniGene: Hs.26988



主站蜘蛛池模板： 久久老子午夜精品无码怎么打| 50路60路老熟妇啪啪| 久久人妻少妇嫩草av蜜桃| 看黄a大片爽爽影院免费无码 | 天下第一社区视频www日本| 日本丶国产丶欧美色综合| 国产av一区二区三区传媒| 亚洲aⅴ综合色区无码一区| 狠狠亚洲婷婷综合色香五月排名| 国产制服丝袜亚洲高清| 亚洲国产欧美中文丝袜日韩| 东北女人啪啪对白| 成人免费777777| 最近中文字幕免费mv在线视频| 久久精品一本到东京热| 女女女女女裸体处开bbb| 国产乱码精品一品二品| 亚洲人成网站18禁止人| 亚洲中文有码字幕日本| 欧美情侣性视频| 国产高清在线a视频大全| 国产未发育呦交视频| 久久亚洲精品成人无码网站夜色 | 成人午夜亚洲精品无码区| 女人下边被添全过视频的网址| 精品国际久久久久999| 天堂在/线资源中文在线8| 日本高清色倩视频在线观看| 欧美性videos高清精品| 一二三四视频在线观看日本| 俄罗斯老熟妇色xxxx| 亚洲中文无码永久免费| 亚洲成年网站青青草原| 亚洲深深色噜噜狠狠网站| 亚洲成av人片在www色猫咪| 亚洲中文字幕无码专区| 变态另类牲交乱| 女人另类牲交zozozo| 人禽杂交18禁网站免费| 欧美中文亚洲v在线| 国产精品无码无卡在线播放|