在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ECSCR Antibody, Biotin conjugated

  • 中文名稱:
    ECSCR兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA007385LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) ECSCR Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ECSCR
  • 別名:
    ECSCR antibody; ECSCR_HUMAN antibody; Endothelial cell-specific chemotaxis regulator antibody; Endothelial cell-specific molecule 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Endothelial cell-specific chemotaxis regulator protein (25-124AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulates endothelial chemotaxis and tube formation. Has a role in angiogenesis and apoptosis via modulation of the actin cytoskeleton and facilitation of proteasomal degradation of the apoptosis inhibitors BIRC3/IAP1 and BIRC2/IAP2.
  • 基因功能參考文獻:
    1. Low expression level of ECSCR is associated with evasive resistance and disease progression in cancer. PMID: 26956051
    2. identification of three novel full-length splice variants potentially encoding different protein isoforms PMID: 23147565
    3. Endothelial cell-specific chemotaxis receptor (ECSCR) enhances vascular endothelial growth factor (VEGF) receptor-2/kinase insert domain receptor (KDR) activation and promotes proteolysis of internalized KDR. PMID: 23393131
    4. ECSM2 modulated bFGF-directed endothelial cell motility via the FGF receptor (FGFR)-extracellular regulated kinase (ERK)-focal adhesion kinase (FAK) pathway. PMID: 21720547
    5. Characterize a novel cell surface protein ECSM2 that regulates endothelial chemotaxis and tube formation, and interacts with filamin A. PMID: 18556573
    6. ECSM2 is involved in cell-shape changes and actin cytoskeletal rearrangement, suppresses tyrosine phosphorylation signaling and ECSM2 can cross-talk with EGFR to attenuate the EGF-induced cell migration. PMID: 19267780
    7. Knockdown of ARIA in HUVECs significantly reduced endothelial apoptosis without affecting either cell migration or proliferation. ARIA knockdown significantly increased inhibitor of apoptosis cIAP-1 and cIAP-2 protein expression PMID: 19416853
    8. Observational study of gene-disease association. (HuGE Navigator) PMID: 19240791

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein. Cytoplasm.
  • 蛋白家族:
    ECSCR family
  • 組織特異性:
    Highest expression in endothelial cells. Also detected in vascular smooth muscle, macrophages, lymphocytes, and mast cells.
  • 數據庫鏈接:

    HGNC: 35454

    KEGG: hsa:641700

    UniGene: Hs.483538



主站蜘蛛池模板: 免费国产乱理伦片在线观看| а天堂中文官网| 97国产精东麻豆人妻电影| 国产在线观看片a免费观看| 日本久久综合久久鬼色| 国产在线永久视频| 人妻少妇精品中文字幕av| 四虎亚洲欧美成人网站| 日韩午夜理论免费tv影院| 亚洲精品av无码喷奶水网站| 精品国产精品国产偷麻豆| 高潮毛片无遮挡高清视频播放 | 亚洲无av码在线中文字幕| 天堂av无码av在线a√| 激情综合婷婷色五月蜜桃| 乱色欧美激惰| 国产美女午夜福利视频| 男人狂躁进女人下面免费视频| 久久精品蜜芽亚洲国产av| 伊人色综合久久天天| 野花在线无码视频在线播放| 2019最新中文字幕在线观看| 中国女人内谢69xxxx视频| 无码国产精品一区二区免费vr| 西西艺术人像摄影| 午夜精品一区二区三区在线视| 天堂√最新版中文在线地址| 国产成人亚洲精品另类动态| 久久996re热这里有精品| 久久国产中文娱乐网| 强伦人妻一区二区三区视频18| 精品国产免费观看久久久| 国精产品一区一区三区有限公司| 国产精品美女久久久久久久| 初尝人妻少妇中文字幕| 狠狠精品久久久无码中文字幕| 国产精品美女久久久久网站浪潮| 国产精品毛片无遮挡高清| 亚洲精品v天堂中文字幕| 潮喷大喷水系列无码久久精品| 成人无码精品一区二区三区亚洲区|