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ECI2 Antibody

  • 中文名稱:
    ECI2兔多克隆抗體
  • 貨號:
    CSB-PA017768GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    2-trans-enoyl-CoA isomerase antibody; ACBD2 antibody; acyl Coenzyme A binding domain containing 2 antibody; D2-enoyl-CoA isomerase antibody; D3 antibody; D3 D2 enoyl CoA isomerase antibody; DBI related protein 1 antibody; DBI-related protein 1 antibody; delta(2)-enoyl-CoA isomerase antibody; Delta(3) antibody; Delta(3) delta(2) enoyl CoA isomerase antibody; Diazepam-binding inhibitor-related protein 1 antibody; Dodecenoyl CoA isomerase antibody; Dodecenoyl-CoA isomerase antibody; DRS 1 antibody; DRS-1 antibody; DRS1 antibody; Eci2 antibody; ECI2_HUMAN antibody; Enoyl-CoA delta isomerase 2 antibody; HCA88 antibody; Hepatocellular carcinoma associated antigen 88 antibody; Hepatocellular carcinoma-associated antigen 88 antibody; mitochondrial antibody; pECI antibody; Peroxisomal 3 antibody; Peroxisomal 3,2-trans-enoyl-CoA isomerase antibody; Peroxisomal D3 D2 enoyl CoA isomerase antibody; Renal carcinoma antigen NY REN 1 antibody; Renal carcinoma antigen NY-REN-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Human PECI
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates.
  • 基因功能參考文獻:
    1. Enoyl-CoA delta isomerase 2 (ECI2) is a novel AR-target that promotes prostate cancer cell survival PMID: 28415728
    2. Ectopic expression of the ACBD2/ECI2 isoform A in MA-10 cells led to increased basal and hormone-stimulated steroid formation, indicating that ACBD2/ECI2-mediated peroxisomes-mitochondria interactions favor in the exchange of metabolites and/or macromolecules between these 2 organelles in support of steroid biosynthesis. Considering the widespread occurrence of the ACBD2/ECI2 protein, we propose that this protein might se PMID: 27167610
    3. Disruption of mitochondrial beta -oxidation of unsaturated fatty acids in the 3,2-trans-enoyl-CoA isomerase-deficient mouse PMID: 11916962
    4. DRS-1 may serve as an autoantigen eliciting immune attack against hematopoietic stem cells in a subset of acquired aplastic anemia patients characterized by increased paroxysmal nocturnal hemoglobinuria-type cells PMID: 15217832
  • 亞細胞定位:
    [Isoform 1]: Mitochondrion.; [Isoform 2]: Peroxisome matrix.
  • 蛋白家族:
    Enoyl-CoA hydratase/isomerase family
  • 組織特異性:
    Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.
  • 數據庫鏈接:

    HGNC: 14601

    OMIM: 608024

    KEGG: hsa:10455

    STRING: 9606.ENSP00000369461

    UniGene: Hs.15250



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