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  4. EBF2 Antibody, FITC conjugated

EBF2 Antibody, FITC conjugated

  • 中文名稱：
    EBF2兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA884503LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EBF2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EBF2
  • 別名：
    EBF2 antibody; COE2Transcription factor COE2 antibody; Early B-cell factor 2 antibody; EBF-2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription factor COE2 protein (53-254AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
  • 基因功能參考文獻：
    1. EBF2 gene variants can contribute to KD [ Kawasaki disease]in the Korean population. PMID: 29749135
    2. Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
    3. Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2, thereby forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype. PMID: 25002143
    4. EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. PMID: 19671856
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    COE family
  • 數據庫鏈接：

    HGNC: 19090

    OMIM: 609934

    KEGG: hsa:64641

    STRING: 9606.ENSP00000430241

    UniGene: Hs.491292



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