在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

E6 Antibody, HRP conjugated

Rare Species
  • 中文名稱:
    E6兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA334186LB01HNY
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Human papillomavirus type 52 E6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    E6 antibody; Protein E6 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human papillomavirus type 52
  • 免疫原:
    Recombinant Human papillomavirus type 52 Protein E6 protein (1-148AA)
  • 免疫原種屬:
    Human papillomavirus type 52
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays a major role in the induction and maintenance of cellular transformation. Acts mainly as an oncoprotein by stimulating the destruction of many host cell key regulatory proteins. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase, and inactivates tumor suppressors TP53 and TP73 by targeting them to the 26S proteasome for degradation. In turn, DNA damage and chromosomal instabilities increase and lead to cell proliferation and cancer development. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT). The resulting increased expression of hTERT prevents the shortening of telomere length leading to cell immortalization. Other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis. E6 also inhibits immune response by interacting with host IRF3 and TYK2. These interactions prevent IRF3 transcriptional activities and inhibit TYK2-mediated JAK-STAT activation by interferon alpha resulting in inhibition of the interferon signaling pathway.
  • 亞細胞定位:
    Host cytoplasm. Host nucleus.
  • 蛋白家族:
    Papillomaviridae E6 protein family


主站蜘蛛池模板: 欧美最新精品videossexohd| 中文字幕人妻无码视频| 唐人社导航福利精品| 久久久久人妻一区精品色欧美| 免费观看的av在线播放| 欧美巨大xxxx做受高清| 欧美一区二区三区性视频| 久久ee热这里只有精品| 国产精品禁18久久久夂久| 50岁熟妇大白屁股真爽| 国产精品内射后入合集| 无码国内精品人妻少妇| 成 人 亚洲 综合天堂| 久久久一本精品久久精品六六| 亚欧av无码乱码在线观看性色| 精品深夜av无码一区二区老年| 日本大片免a费观看视频| 老熟妇乱子交视频一区| 亚洲精品无码mv在线观看网站| 国产亚洲欧美精品永久| 天堂网在线.www天堂在线资源| 美女张开腿黄网站免费下载| 久久綾合久久鬼色88| 欧美精品久久96人妻无码| 国产成人片无码视频在线观看| 少女韩国电视剧在线观看完整| 国产亚洲欧美另类一区二区| 中文字幕av无码不卡免费| 国产精品免费无码二区| 国内揄拍高清国内精品对白| 国产成人无码av在线影院| 亚洲kkk4444在线观看| 国色天香社区视频| 污污污污污污www网站免费| 色五月丁香五月综合五月4438| 亚洲男人综合久久综合天堂| 嫩草研究院久久久精品| 亚洲精品成人区在线观看| 欧美亚洲国产成人一区二区三区| 2020最新无码福利视频| 国内精品伊人久久久久妇|