在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DYNLRB1 Antibody, FITC conjugated

DYNLRB1 Antibody, FITC conjugated

  • 中文名稱：
    DYNLRB1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA865093HC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DYNLRB1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DYNLRB1
  • 別名：
    DYNLRB1 antibody; BITH antibody; DNCL2A antibody; DNLC2A antibody; ROBLD1 antibody; HSPC162Dynein light chain roadblock-type 1 antibody; Bithoraxoid-like protein antibody; BLP antibody; Dynein light chain 2A antibody; cytoplasmic antibody; Dynein-associated protein Km23 antibody; Roadblock domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Dynein light chain roadblock-type 1 protein (3-96AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
  • 基因功能參考文獻：
    1. Human colorectal carcinoma cells display decreased tumor progression and invasion when a novel anti-cell motility target, DYNLRB1, is being silenced. PMID: 23755307
    2. TGFbeta regulates km23-1 interaction with the R1beta regulatory subunit of protein kinase A. PMID: 23333499
    3. these findings demonstrate that km23-1 regulates RhoA and motility-associated actin modulating proteins, suggesting that km23-1 may represent a novel target for anti-metastatic therapy. PMID: 23079622
    4. km23-1 is required for TGFbeta1 autoinduction through Smad2-independent Ras/ERK/JNK pathways PMID: 22637579
    5. Silencing of km23, either through somatic genetic mutation or promoter hypermethylation, is rare in ovarian, breast, and colorectal cancers. PMID: 16778097
    6. report the 2.1-A crystal structure of Dnlc2A using single anomalous diffraction PMID: 16970917
    7. Infrequently mutated in human colorectal and gastric cancers. PMID: 17556076
    8. DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi. PMID: 18044744
    9. Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier. PMID: 19571232

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    GAMAD family
  • 組織特異性：
    High expression in heart, liver, brain and pancreas; moderate in placenta, skeletal muscle and kidney; low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients.
  • 數據庫鏈接：

    HGNC: 15468

    OMIM: 607167

    KEGG: hsa:83658

    STRING: 9606.ENSP00000349679

    UniGene: Hs.593920



主站蜘蛛池模板： 少妇太爽了在线观看| 人妻精品久久无码区| 极品少妇一区二区三区四区| 少妇扒开腿让我爽了一夜| 日日噜噜噜夜夜爽爽狠狠视频| 狠狠色丁香婷婷综合尤物 | 国产成人亚洲综合| 无码人妻久久一区二区三区蜜桃| 中文无码字幕中文有码字幕| 成人h无码动漫超w网站| 无码人妻丰满熟妇区96| 欧美性大战久久久久久| 青青草无码免费一二三区| 日本高清二区视频久二区| 精品人妻少妇一区二区三区| 麻豆果冻传媒精品| 亚洲龙腾成小说人网| 精品一区二区三区在线播放视频| 无码国产精品一区二区免费式影视| 日韩精品中文字幕无码一区| 国产精品va尤物在线观看| 午夜无码成人免费视频| 中文字幕人成乱码在线观看| 97人妻无码一区二区精品免费| 男女做爰猛烈啪啪吃奶动| 国产在线精品一区二区三区| 精品久久久久久中文字幕| 精品亚洲国产成人av在线时间短的| 国产婷婷丁香五月缴情成人网| 自拍偷自拍亚洲精品播放 | 亚洲中文字幕无码爆乳av | 丰满五十六十老熟女hd| 色欲aⅴ亚洲情无码av蜜桃| 人妻老妇乱子伦精品无码专区 | 亚洲综合天堂av网站在线观看 | 欧美黑人xxxx又粗又长 | 无码熟妇人妻av在线电影| 久久久亚洲精华液精华液精华液 | 精品成在人线av无码免费看| 久久婷婷激情综合色综合俺也去 | 无码aⅴ精品一区二区三区|