在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DUSP16 Antibody

  • 中文名稱:
    DUSP16兔多克隆抗體
  • 貨號:
    CSB-PA887158ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: DUSP16 antibody at 1.69µg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 74, 17 kDa
      Observed band size: 74 kDa
    • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA887158ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA887158ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DUSP16 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Dual specificity phosphatase 16 antibody; Dual specificity protein phosphatase 16 antibody; DUS16_HUMAN antibody; DUSP 16 antibody; DUSP16 antibody; KIAA1700 antibody; MAP kinase phosphatase 7 antibody; MAPK phosphatase 7 antibody; Mitogen activated protein kinase phosphatase 7 antibody; Mitogen-activated protein kinase phosphatase 7 antibody; MKP 7 antibody; MKP-7 antibody; MKP7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dual specificity protein phosphatase 16 protein (416-665AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
  • 基因功能參考文獻:
    1. The crystal structure of JNK1 bound to the catalytic domain of MKP7 at 2.4-A resolution, providing high-resolution structural insight into the FXF-docking interaction, is reported. PMID: 26988444
    2. The DUSP16 ablation leads to a G1/S transition arrest, reduced incorporation of 5-bromodeoxyuridine, enhanced senescence-associated beta-galactosidase activity, and formation of senescence-associated heterochromatic foci. PMID: 26381291
    3. analysis of the interaction of the MAPK binding domain of DUSP16 with p38alpha PMID: 23926106
    4. PPARdelta-mediated messenger RNA stabilization of mitogen-activated protein kinase phosphatase (MKP)-7 was responsible for the GW501516-mediated inhibition of JNK signaling. PMID: 23639976
    5. Data indicate that the activities of phosphoprotein phosphatases MKP5 and MKP7 were determined in the system. PMID: 23233447
    6. MKP-7, a negative regulator of JNK, regulates VCAM-1 expression in activated endothelial cells through IRF-1 but not GATA6. PMID: 22182512
    7. DUSPs 10 and 16 are positive regulators of activation, apparently acting by modulating cross-talk between the p38 and ERK pathways. PMID: 22245064
    8. DUSP16 is a new epigenetically regulated determinant of JNK activation in BL. PMID: 20551953
    9. MKP-7 down-regulates ERK-dependent gene expression by blocking nuclear accumulation of phospho-ERK. PMID: 20122898
    10. context-dependent role for DUSP16 on cell transformation and apoptosis. PMID: 14586399
    11. activation of the ERK pathway strongly blocks JNK activation through stabilization of MKP-7 mediated by phosphorylation PMID: 15689616
    12. MKP7 binds beta-arrestin 2 via amino acids 394-443 of MKP7, the same region that interacts with JIP-1 PMID: 15888437
    13. identification of an intricate SDF-1alpha-induced signaling cascade that involves eNOS, JNK3, and MKP7and enhances endothelial migration PMID: 19307591

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasmic vesicle. Note=After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles.
  • 蛋白家族:
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 數據庫鏈接:

    HGNC: 17909

    OMIM: 607175

    KEGG: hsa:80824

    STRING: 9606.ENSP00000228862

    UniGene: Hs.536535



主站蜘蛛池模板: 九九99精品久久久久久综合| 国产草草影院ccyycom| 精品久久久久久久无码| 揉着我的奶从后面进去视频| 一本大道无码人妻精品专区| 99国产精品国产精品九九| 美女张开腿黄网站免费下载| 亚洲vav在线男人的天堂| 日韩精品人妻无码久久影院| 粗大的内捧猛烈进出少妇视频| 无码人妻丝袜视频在线播免费| 夜夜爱夜鲁夜鲁很鲁| 亚洲男女一区二区三区| 精品人妻人人做人人爽| 男人扒开女人内裤强吻桶进去 | 女人高潮内射99精品| 中文字幕乱码一区av久久不卡| 国产成人亚洲高清一区| 在线观看无码av网站永久免费| 中文毛片无遮挡高潮免费| 免费午夜爽爽爽www视频十八禁 | 台湾无码一区二区| 麻豆果冻传媒精品| 国产精品激情欧美可乐视频| 亚洲乱码日产精品bd在| 蜜桃mv在线播放免费观看视频 | 色综合色狠狠天天综合网| 国内偷窥一区二区三区视频| 内射白嫩少妇超碰| 无码毛片视频一区二区本码| 欧美国产日产一区二区| 国产97人人超碰caoprom| 中国少妇videos呻吟| 无码人妻h动漫| 精品无码国产av一区二区| 欧美色欧美亚洲另类二区| 日本欧美一区二区三区在线播放| 国产啪精品视频网站免费尤物| 性色av免费网站| 无码人妻精品一区二区三| 无码熟妇人妻av在线影片免费|