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DUSP15 Antibody, FITC conjugated

  • 中文名稱(chēng)：
    DUSP15兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA861994LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) DUSP15 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DUSP15
  • 別名：
    bA243J16.5 antibody; Chromosome 20 open reading frame 57 antibody; Dual specificity phosphatase 15 antibody; Dual specificity phosphatase like 15 antibody; Dual specificity protein phosphatase 15 antibody; DUS15_HUMAN antibody; DUSP15 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ20645 antibody; Vaccinia virus VH1 related dual specific protein phosphatase Y antibody; Vaccinia virus VH1-related dual-specific protein phosphatase Y antibody; VH1 related member Y antibody; VH1-related member Y antibody; VHY antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Dual specificity protein phosphatase 15 protein (1-295AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6.; May play a role in the regulation of oligodendrocyte differentiation. May play a role in the regulation of myelin formation. Involved in the regulation of Erk1/2 phosphorylation in Schwann cells; the signaling may be linked to the regulation of myelination.
  • 基因功能參考文獻(xiàn)：
    1. The results showed that dual specificity phosphatase 15 (DUSP15) rs3746599 was significantly associated with autism under allelic, additive and dominant models,The findings initially suggest that DUSP15 might be a susceptibility gene for autism in Chinese Han population. PMID: 27223645
    2. Dusp15/VHY is a key regulator of oligodendrocyte differentiation, and PDGFR-beta and SNX6 are novel and specific Dusp15 substrates. PMID: 22792334
    3. VHY is a new member of a subgroup of myristoylated VH1-like small dual specificity phosphatases PMID: 15138252
    4. crystal structure of catalytic domain PMID: 16170801
  • 亞細(xì)胞定位：
    Cytoplasm.; [Isoform 3]: Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 組織特異性：
    Highly expressed in testis. Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 16236

    OMIM: 616776

    KEGG: hsa:128853

    STRING: 9606.ENSP00000341658

    UniGene: Hs.434108



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