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DUSP13 Antibody, HRP conjugated

  • 中文名稱：
    DUSP13兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA883436LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DUSP13 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DUSP13
  • 別名：
    DUSP13 antibody; DUSP13B antibody; TMDPDual specificity protein phosphatase 13 isoform B antibody; DUSP13B antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Dual specificity phosphatase SKRP4 antibody; Testis- and skeletal-muscle-specific DSP antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Dual specificity protein phosphatase 13 isoform B protein (1-198AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
  • 基因功能參考文獻：
    1. data suggest an important role for DUSP13B in protection from external stress during spermatogenesis PMID: 21360282
    2. identified a gene on chromosome 10q22.2 using alternative ORFs to encode two distinct DSPs: the testis and skeletal muscle-specific TMDP and a novel muscle-restricted DSP(MDSP) PMID: 15252030
    3. Here, we report the crystal structure of human TMDP at a resolution of 2.4 A. In spite of high sequence similarity with other DSPs, the crystal structure of TMDP shows distinct structural motifs and surface propertie PMID: 17044055
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 組織特異性：
    Highly expressed in the testis (at protein level). Also found in the skeletal muscle.
  • 數據庫鏈接：

    HGNC: 19681

    OMIM: 613191

    STRING: 9606.ENSP00000452702

    UniGene: Hs.178170



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