在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DTNA Antibody

  • 中文名稱:
    DTNA兔多克隆抗體
  • 貨號:
    CSB-PA007216GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DTNA
  • 別名:
    Alpha-dystrobrevin antibody; D18S892E antibody; DRP3 antibody; DTN antibody; DTN-A antibody; DTNA antibody; DTNA_HUMAN antibody; Dystrobrevin alpha antibody; Dystrophin related protein 3 antibody; Dystrophin-related protein 3 antibody; FLJ96209 antibody; LVNC1 antibody; OTTHUMP00000163151 antibody; OTTHUMP00000163152 antibody; OTTHUMP00000163153 antibody; OTTHUMP00000163154 antibody; OTTHUMP00000163155 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DTNA
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors.
  • 基因功能參考文獻:
    1. Report left ventricular non-compaction associated with Barth Syndrome due to triple mutations in TAZ, DTNA, and SDHA genes in multiple members of one family. PMID: 29508483
    2. we show for the first time localization of alpha-DB2 in nucleoli and Cajal bodies and provide evidence that a-DB2 is involved in the structure of nucleoli and might modulate nucleolar functions PMID: 25959029
    3. our findings suggest that novel mutations in FAM136A and DTNA genes are probably causal variants in FMD. PMID: 25305078
    4. apoptosis-induction in HL-60 cells involves not only classical markers of apoptosis but also a network alpha-DB-associated proteins at the cell membrane, the cytoplasm and nucleus, affecting key cellular transport processes and cellular structure. PMID: 22507200
    5. Results suggest that alpha-dystrobrevin isoforms play a central role in cytoskeleton reorganization via their multiple interactions with actin and actin-associating proteins. PMID: 20111909
    6. Data show that alpha-dystrobrevin-1 recruits alpha-catulin, which supersensitizes alpha(1D)-AR functional responses by recruiting effector molecules to the signalosome. PMID: 21115837
    7. Fundamental functional differences between the alpha-dystrobrevins of mice and humans raises questions about the use of the mouse as a model animal for Duchenne muscular dystrophy. PMID: 19961569
    8. During a cycle of regeneration in tibialis anterior muscle following myonecrosis, alpha-dystrobrevin reaches 50% of the protein level on day 28 by 6.6 days, regenerating more slowly than dystrophin. PMID: 12416719
    9. alpha-dystrobrevin and its splice isoforms have a role in signal transduction in myeloid cells during induction of granulocytic differentiation and/or at the commitment stage of differentiation or phagocytic cells PMID: 12475945
    10. Transgenic expression of either isoform of alpha-dystrobrevin prevented muscle fiber degeneration in knockout mice; however, only alphaDB1 corrected defects at neuromuscular and musculotendinous junctions. PMID: 12604589
    11. patients with deficiency of beta2-syntrophin and alpha-dystrobrevin presented with severe congenital weakness and died in the first year, and patients with deficiency of alpha-DNT had congenital muscular dystrophy with complete external ophthalmoplegia. PMID: 12899872
    12. findings suggest that a-dystrobrevin specifically is associated with the tight junctions during their reorganization PMID: 15834686
    13. Results confirm that dystrophin is required for anchorage of the syntrophin-dystrobrevin subcomplex and suggest that expression of the syntrophin-dystrobrevin complex may be independently regulated through neuromuscular transmission. PMID: 15835271
    14. Dystrobrevin mRNA including exons 11A and 12 was increased in both skeletal and cardiac muscle of DM1 patients. The aberrantly spliced alpha-dystrobrevin isoform was localized to the sarcolemma. PMID: 18299519

    顯示更多

    收起更多

  • 相關疾病:
    Left ventricular non-compaction 1 (LVNC1)
  • 亞細胞定位:
    Cytoplasm. Cell junction, synapse. Cell membrane.
  • 蛋白家族:
    Dystrophin family, Dystrobrevin subfamily
  • 組織特異性:
    Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle.
  • 數據庫鏈接:

    HGNC: 3057

    OMIM: 601239

    KEGG: hsa:1837

    STRING: 9606.ENSP00000382064

    UniGene: Hs.643454



主站蜘蛛池模板: 欧美综合自拍亚洲综合图片区| 亚洲粉嫩高潮的18p| 女人被狂躁c到高潮喷水电影| 国产麻豆精品传媒av国产婷婷| 国产区精品一区二区不卡中文| 无码专区丰满人妻斩六十路| 日本特黄aaaaaa大片| 中文乱码免费一区二区三区 | 亚洲精品乱码久久久久久蜜桃| 男人扒女人添高潮视频| 少妇被粗大的猛进69视频| 色综合天天综合天天更新| 疯狂迎合进入强壮公的视频| 96亚洲精华国产精华精华液| 日韩内射美女人妻一区二区三区| 精品久久国产字幕高潮| 成 人 在 线 免费观看| 亚洲精品日韩一区二区小说| 国产精品无码久久四虎| 日本高清一区二区三| 5个黑人躁我一个视频| 无码av免费毛片一区二区| 午夜a理论片在线播放| 国产区在线观看成人精品| 自拍偷自拍亚洲精品播放| 99久久婷婷国产综合精品青草免费 | 国产精品久久久久久爽爽爽床戏| 国产福利酱国产一区二区| 99精品国产一区二区三区不卡| 草草久久久无码国产专区| 香蕉成人伊视频在线观看| 青青青青国产免费线在线观看| 国产内射一区亚洲| 好紧好湿好黄的视频| 欧美午夜特黄aaaaaa片| 黑色丝袜脚足国产在线看| 五月综合缴情婷婷六月| 极品新婚夜少妇真紧| 中字幕人妻一区二区三区| 欧美村妇激情内射| 国产亚洲久久久久久久|