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  4. DPH3 Antibody, Biotin conjugated

DPH3 Antibody, Biotin conjugated

  • 中文名稱：
    DPH3兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA822214LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DPH3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DPH3
  • 別名：
    DPH3 antibody; DESR1 antibody; ZCSL2DPH3 homolog antibody; CSL-type zinc finger-containing protein 2 antibody; DelGEF-interacting protein 1 antibody; DelGIP1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human DPH3 homolog protein (1-82AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).; Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.
  • 基因功能參考文獻：
    1. The results from this study show occurrence of frequent somatic non-coding mutations adjacent to a pre-existing binding site for Ets transcription factors within the directional promoter of DPH3 and OXNAD1 genes in three major skin cancers. PMID: 26416425
    2. DelGIP1is a binding partner of deafness locus putative guanine nucleotide exchange factor; downregulation of DelGIP1 induced increased extracellular secretion of proteoglycans indicating a possible role for DelGIP1 in the secretion process PMID: 14980502
    3. Solution structure of human DESR1, a CSL zinc-binding protein. PMID: 18214955
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DPH3 family
  • 組織特異性：
    Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.
  • 數據庫鏈接：

    HGNC: 27717

    OMIM: 608959

    KEGG: hsa:285381

    STRING: 9606.ENSP00000419599

    UniGene: Hs.388087



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