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DPH3 Antibody, Biotin conjugated

  • 中文名稱:
    DPH3兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA822214LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DPH3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DPH3
  • 別名:
    DPH3 antibody; DESR1 antibody; ZCSL2DPH3 homolog antibody; CSL-type zinc finger-containing protein 2 antibody; DelGEF-interacting protein 1 antibody; DelGIP1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human DPH3 homolog protein (1-82AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).; Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.
  • 基因功能參考文獻:
    1. The results from this study show occurrence of frequent somatic non-coding mutations adjacent to a pre-existing binding site for Ets transcription factors within the directional promoter of DPH3 and OXNAD1 genes in three major skin cancers. PMID: 26416425
    2. DelGIP1is a binding partner of deafness locus putative guanine nucleotide exchange factor; downregulation of DelGIP1 induced increased extracellular secretion of proteoglycans indicating a possible role for DelGIP1 in the secretion process PMID: 14980502
    3. Solution structure of human DESR1, a CSL zinc-binding protein. PMID: 18214955
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    DPH3 family
  • 組織特異性:
    Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.
  • 數據庫鏈接:

    HGNC: 27717

    OMIM: 608959

    KEGG: hsa:285381

    STRING: 9606.ENSP00000419599

    UniGene: Hs.388087



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