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  4. DOT5 Antibody

DOT5 Antibody

Rare Species
  • 中文名稱：
    DOT5兔多克隆抗體
  • 貨號：
    CSB-PA328135XA11SVG
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: DOT5 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 25 kDa
      Observed band size: 25 kDa
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DOT5
  • 別名：
    Peroxiredoxin DOT5 (Prx) (EC 1.11.1.15) (Disrupter of telomere silencing protein 5) (Nuclear thiol peroxidase) (nTPx) (Thioredoxin peroxidase), DOT5
  • 反應種屬：
    S. cerevisiae
  • 免疫原：
    Recombinant S. cerevisiae DOT5 protein (37-118aa)
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Affinity-chromatography
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Has a role in telomere silencing, which is the repression of chromatin structure which leads to a stop in the transcription of nearby genes. Also has a role in the regulation of telomere length. Acts as an alkyl-hydroperoxide reductase in the nucleus during post-diauxic growth. Preferentially reduces alkyl-hydroperoxides rather than hydrogen peroxide. Acts as an antioxidant necessary for stationary phase survival.
  • 基因功能參考文獻：
    1. X-ray analysis of a truncated mutant of yeast nuclear thiol peroxidase, a novel atypical 2-Cys peroxiredoxin PMID: 16511121
  • 亞細胞定位：
    Nucleus. Chromosome, telomere.
  • 蛋白家族：
    Peroxiredoxin family, BCP/PrxQ subfamily
  • 數據庫鏈接：

    KEGG: sce:YIL010W

    STRING: 4932.YIL010W



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