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  4. DOK6 Antibody

DOK6 Antibody

  • 中文名稱：
    DOK6兔多克隆抗體
  • 貨號：
    CSB-PA007112GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DOK6
  • 別名：
    DOK6 antibody; DOK5LDocking protein 6 antibody; Downstream of tyrosine kinase 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DOK6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
  • 基因功能參考文獻：
    1. DOK-6 is involved in RET signaling with less influence when compared with DOK-1, DOK-4, and SHC. PMID: 20210798
    2. Dok-6 binds to the phosphorylated Ret Tyr(1062) residue resulting in phosphorylation of tyrosine residue(s) located within the unique C terminus of Dok-6 predominantly through a Src-dependent mechanism PMID: 15286081
  • 蛋白家族：
    DOK family, Type B subfamily
  • 組織特異性：
    Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
  • 數據庫鏈接：

    HGNC: 28301

    OMIM: 611402

    KEGG: hsa:220164

    STRING: 9606.ENSP00000372160

    UniGene: Hs.278285



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