在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DOK4 Antibody

DOK4 Antibody

  • 中文名稱：
    DOK4兔多克隆抗體
  • 貨號(hào)：
    CSB-PA548346
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from 293 cells and mouse lung cells, using DOK4 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DOK4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DOK4
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human DOK4.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
  • 基因功能參考文獻(xiàn)：
    1. the current study have explored in more detail the structure and function of the Dok-4 PTB domain. PMID: 22982678
    2. DOK4 expression in human T cells has been demonstrated, and its genomic structure has been predicted. PMID: 12595900
    3. IRS5/DOK4 and IRS6/DOK5 represent two new signaling proteins with potential roles in insulin and IGF-1 action PMID: 12730241
    4. Results suggest that Dok-4, through activation of the Rap1-ERK1/2 pathway, regulates GDNF-mediated neurite outgrowth during neuronal development. PMID: 16820412
    5. IRS-5 (DOK4) is significantly upregulated in 90% of examined clear cell RCCs. Studies on this gene has shown that it is regulated through chromatin remodeling in kidney cells PMID: 17443497
    6. Epigenetic regulation of DOK4 expression is associated with non-small-cell lung cancer. PMID: 19073520
    7. Dok-4 represents a novel negative regulator of T cells PMID: 19494292

    顯示更多

    收起更多

  • 蛋白家族：
    DOK family, Type B subfamily
  • 組織特異性：
    Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19868

    OMIM: 608333

    KEGG: hsa:55715

    STRING: 9606.ENSP00000344277

    UniGene: Hs.279832



主站蜘蛛池模板： 国产精品无需播放器在线观看| 无码人妻精品一区二区在线视频| 久久国产精品福利一区二区三区| 久久亚洲精品成人av无码网站| 欧洲一卡2卡3卡4卡国产| 欧美黑人又粗又大xxx| 久久不见久久见www电影免费| 日产精品久久久一区二区| 国产999精品久久久久久| 色窝窝色蝌蚪在线视频| 一本久道久久综合久久爱| 日本亚洲欧美综合在线| 久久久久99精品国产片| 国产精品交换| 在线精品动漫一区二区无码| 亚洲春色av无码专区在线播放| 97免费人妻在线视频| 久久久久国产精品嫩草影院 | 高大丰满熟妇丰满的大白屁股| 日本高清一二三不卡区| 99精品国产福利一区二区| 国产在线观看无码免费视频| 国产精品后入内射日本在线观看| 国产高清视频一区三区| 国产av老师丝袜美腿丝袜| 日本 精品 高清不卡| 欧美xxxxx高潮喷水| 夜夜躁狠狠躁2021| 一本久道久久综合狠狠老| 丰满熟女高潮毛茸茸欧洲视频| 国产亚洲精品精华液| 熟妇人妻无码中文字幕老熟妇| 久久婷婷五月综合色d啪| 欧美白丰满老太aaa片| 人妻在线日韩免费视频| 波多野42部无码喷潮在线| 国产成人剧情av麻豆果冻| 国产精品无码嫩草地址更新| 欧美老熟妇videos极品另类| 中文字幕一区二区人妻电影| 精品国产高清自在线一区二区|